Flashcards in Diagnostic Imaging EBM Deck (28):
What are the SIRS criteria?
1. temp> 38C (100.4F) or less than 36C
2. HR> 90
3. RR>20 or PaCO2 less than 32
4. WBC 12,000 or 10% bands
What is the Patzakis classification?
Zone 1- forefoot (met necks distally)
Zone 2- midfoot(distal end of calc to met necks)
Zone 3- rearfoot (overlies calcaneus)
Which region in the foot is most common and has greatest risk for osteomyelitis according to Patzakis?
Zone 1- forefoot (metatarsal necks distally)
*rearfoot is next most common and then midfoot
What is the generic name for Primaxin?
Why is Cilstatin combined with imipenem?
bc Cilstatin, is a renal dihydropeptidase inhibitor that prevents hydrolysis and inactivation of imipenem in the kidney
What is the dosage of Primaxin?
500mg q6-8hr IV
what are the 3 FDA-approved abx for treatment of complicated SSTI including diabetic foot infections?
what is the advantage of Ertapenem over Primaxin?
the once daily dosing
(1g q24 hr IV/IM)
What are the common organisms found in human and animal bite wounds?
What is the DOC for human/animal bite wounds?
What abx cover VRE (vancomycin-resistant enterococcus)?
What is the dosage for Nafcillin?
1-2g IV q4-6hr
what are some unique pharmacologic properties of nafcillin?
it is metabolized by the liver!
DOC for MSSA
what is the dosage for Dicloxacillin?
200-500mg PO BID- QID
What is the dosage for Zosyn?
3.375 g IV q6hr
What is the advantage of Zosyn over Unasyn/
Zosyn has pseudomonas coverage while Unasyn does not
What is the dosage for Unasyn?
1.5-3.0g IV q6hr
What are the criteria for AKI?
(changes occur within 48 hrs)
-Creatinine rises >0.3mg/dL or >50% from baseline
-urine output of 6h
What is the normal reference range for BUN/Cr?
Cr- 0.7-1.3 mg/dL
what are normal reference ranges for ESR and CRP?
what are the indications for acute hemodialysis?
A-acidosis: metabolic, unresponsive to other therapy
E-electrolytes: K+ most commonly, phosphorous, Na+
I- ingestion: alcohol (methanol, ethylene glycol), meds (ASA, digoxin)
O-overload of fluids not responsive to diuretics
U- uremia: serositis (pericarditis, pleuritis), encephalopathy, bleeding
What is Bactrim used for?
What is the dosage for Bactrim?
5:1 ratio of SMP to TMP
800mg SMX; 160mg TMP
What are the 2 golden rules for surgical prophylaxis?
1. abx should have achieved its max. concentration at the time of incision/insult
2. abx should cover the most likely organism that would be found if infection were to ensue
what are the indications for surgical prophylaxis?
Name the macrolides.
What is the dosage for Vancomycin?
1g IV q12hrs (for severe infections)
125mg PO q6 hrs (for C. diff colitis)