Diazepam, Midazolam, & Acepromazine

Question 1

Midazolam
1. Use (2)
2. Dose range
3. Side effects (4-7)

Answer 1

1. Anti-seizure, induction
2. 0.5mg/kg
3. Sedation, Ataxia, Respiratory depression, Hypotension, Bradycardia.
   - Paradoxical reactions!! (agro, hyperactive)
   - Nausea/vomiting

Question 2

Midazolam
1. Contraindications (3-5)
2. Drug class
3. Reversal (if applicable)

Answer 2

1. Respiratory depression, Liver dysfunction, Shock/coma
   - Geriatrics
   - Hypersensitivity to benzo’s
2. Benzodiazepine
3. Flumazenil

Question 3

Diazepam
1. Use
2. Dose range
3. Side effects (3-5)

Answer 3

1. Anti-seizure
   - Pre-anes
2. 0.5mg/kg
3. Sedation, Ataxia, Resp depression, Hypotension, Hepatotoxicity

Question 4

Diazepam
1. Contraindications (3-4)
2. Drug class
3. Reversal (if applicable)

Answer 4

1. Liver disease, Resp compromise, Pregnancy.
   - Hypersensitivity to benzo’s
   - May cause liver failure in felines (oral)
2. Benzodiazepine Tranquilizer
3. Flumazenil

Question 5

Acepromazine
1. Use (2)
2. Dose range
3. Side effects (3-4) H.H.B.

Answer 5

1. Sedation (pre-anes, tranquilization), motion sickness/anxiety
2. 0.01-0.05mg/kg
3. Hypotension, Hypothermia, Bradycardia
   - Prolapsed nictitating membrane/penile

Question 6

Acepromazine
1. Contraindications (4-6)
2. Drug class

Answer 6

1. Liver dysfunction, Dehydration, Shock, Cardiac issues, Seizure prone
   - Breeds: BOXERS and giant breeds (v sensitive).
2. Phenothiazine tranquilizer