Methadone, Butorphanol, & Sucralfate

Question 1

Butorphanol
1. Uses (2)
2. Dose range
3. Side effects (4-6)

Answer 1

1. Sedation (no analgesia), mild to moderate pain
   - Cough suppressant
2. Range: 0.1-0.4mg/kg
3. Sedation, Bradycardia, Resp depression, Ataxia
   - Dilated pupils in cats
   - High doses: CNS effects such as seizures, cardiovascular changes, and respiratory depression

Question 2

Butorphanol
1. Contraindications (3)
2. Drug class
3. Reversal (if applicable)

Answer 2

1. HyperTension, Liver disease, Head trauma
2. Opioid analgesic
3. Naloxone

Question 3

Sucralfate
1. Uses (2)
2. Dose range
3. Side effects (2)

Answer 3

1. GI ulcers, mucosal protection (“band aid” for ulcers)
2. 0.5-1mg/kg ?
3. Constipation, Interfere with other oral meds absorption
   - Less common: vomiting

Question 4

Sucralfate
1. Contraindications (2)
2. Drug class

Answer 4

1. Constipation, Pt on concurrent oral meds
   - Known hypersensitivity (rare)
2. GI protectant; Mucosal protective drugs

Question 5

Methadone
1. Uses (2)
2. Dose range
3. Side effects (4)

Answer 5

1. Moderate to severe pain, sedation
   - Pre-med for anesthesia (analgesic effects).
2. 0.1-0.5mg/kg
3. Sedation, Resp depression, Bradycardia, Urinary/Pupil retention.
   - Less common: vomiting

Question 6

Methadone
1. Contraindications (2)
2. Drug class
3. Reversal (if applicable)

Answer 6

1. Head trauma, Resp depression
   - Pregnancy
2. Opioid analgesic
   - Also, NMDA receptor antagonist activity
3. Naloxone
   - Butorphanol is a partial reversal

Question 7

Butorphanol Contraindications (3)
(8 less common)

Answer 7

1. Hypertensive patients
2. Liver disease
3. Head trauma or CNS issues

Less common:
- Severe kidney impairment
- Addison’s disease
- Lower respiratory tract disease
- Heartworm disease
- Geriatric or severely debilitated patients
- Hypothyroidism.
- Hypersensitivity to opioids
- Pregnant or nursing Pts