Digestion and Transport of Dietary Lipids Flashcards

(61 cards)

1
Q

What is a triacyglycerol ? What is the purpose ?

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2
Q

What are the TAG hydrolyzes to, and where ?

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3
Q

What is bile salt? What is it made of? what does it do ? what acts on the gallbladder?

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4
Q

What is pancreatic lipase for ? What does it break ?

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5
Q

The pancreatic lipase , what happens in response to acidic material ? What does secretin singal ? What is the purpose of bicarbonate ? What is the purpose of colipase ? What is the role of lipase ?

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6
Q

What is a orlistat ? What does it inhibit ?

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7
Q

know this

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8
Q

What is short and medium chain fatty acids influence with bile salt ? Where are they absorbed? Where does it enter and how is it transported to the liver ?

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9
Q

Know this

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10
Q

What are chylomicrons ? What happens after lipase hydrolyzes ?

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11
Q

What are chylomicrons composed of ?

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12
Q

How are chylomicrons transported ?

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13
Q

know the fate of chylomicrons ?

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14
Q

know the absorption of food lipids

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15
Q

What is the major source of carbon for the synthesis

of fatty acids ? Where does it occur? what is glucose converted ? What does the product useful for ?

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16
Q

What is the conversion of glucose to Acetyl -CoA ? Where does it begin ?

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17
Q

What happens to the acetyl CoA are high ? What is citrate cleaved from , and what does form? What is the role of pyruvate dehydrogenase ? What is the role of NADPH required for ?

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18
Q

How are Oxaloacetate is converted to pyruvate ? What are the two stops ?

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19
Q

What is the formation of malonyl-CoA for ? What is the purpose of Acetyl CoA carboxilase enzyme

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20
Q

Know the regulation of Acetyl - CoA carboxylase ?

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21
Q

What does prolong consumption of a diet containing excess calories cause ?

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22
Q

For the synthesis of long chain fatty acids, what happens when malonyl -coA synthesized ?

What happens to each passage through the cycle ?

What happens when the chain reaches 16 carbons ?

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23
Q

For Fatty acid synthase complex , the large enzyme composed of ?

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24
Q

For Fatty acid Synthase complex, what is needed to initiate FA biosynthesis ?

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25
In Step 1, Acetyl-CoA is transferred to ? What does Malonyl-CoA attached to ? What does acetyl and malonyl moieties condense ?
26
In step 2, what happens in the b-keto group ?
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In the step 3, the elimination of water creates ?
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Step 4, the double bond is reduced to ?
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In repetition, the 4C fatty acyl chain is
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For fatty acids synthesis note, where does it take place ? What are the intermediate attached to? What happens in higher organism ? What happens to the activated donor ? What is fatty acid reduction ? When does it stop?
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In elongation, palmiate is activated to form ? The long chain fatty acids can be elongated in two carbons at ?
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Desaturation, where does it occur ? The most common is the placement of ?
33
The essential fatty acids, the mammals cannot incorporate a ?
34
What is the Linoleic acid for ? What does it bind to ?
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The fate of fatty acids, What happens to most of the FA? what are the two fates ?
36
Triacylglycerol, where is the glycerol-3-phosphate produced ? Where does glycerol-3-phosphate reacts with ? what happens to phosphatidic acid ?
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For storage, what kind of tissue? Where are LPL digest ? Where do FA enter ?
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Release, what happens in lipolysis ? What is hormone sensitive lipase ?
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For release of fatty acids, what does it utilize ? What does it activate ? know it
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.
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To release of fatty acids know it
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The B-Oxidation of fatty acids, is a process by which fatty acids are degraded by ? The B-Oxidation occurs in the ? The 2-C units are released as ?
43
Activation of Fatty acids, the Acyl-CoA synthease condenses ? The formation of a Coa ester is ?
44
Transport of Fatty acids into Mitochondria, where does B-Oxidation occur ? Where are Acyl-CoA are converted to ? The translocator then imports ?
45
In Deficiencies of Carnitine of Carnitine transferase or translocator, What are the symptoms include ? What tissue and organ does it effect ?
46
For B-Oxidation of fatty acids it involves ? Fatty acid oxidase are found in ?
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Acyl-CoA Dehydrogenase, what does the mechanism involves ?
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For Enoyl-CoA Hydratase, what is the water for ? What does it use the substrate with ?
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Hydroxyacyl-CoA dehydrogenase, oxidizes tge B-Hydroxyl group to ? The enzyme is completely specific ?
50
In thiolase, the nucleophilic sulhydryl group of CoA-SH attaks the ?
51
The B-Oxidation, the four steps of B-Oxidation are repeate to get FA ?
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Generation of ATP
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B-Oxidation of Odd Chain FA, the odd chain fatty acids are less ? The B-Oxidation occurs pretty much ?
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B-Oxidation of Unsaturated FA
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know it
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Ketone bodies what is it for?
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Ketone bodies and Diabetes are ?
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