DNA Replication

Question 1

What charge do dna and RNA have ? What are the basic units or nucleoides that are found in dna or RNA ?

What is a nucleotide or nucleoside ?

Answer 1

Question 2

Each nucloeotide has three parts, what are they ?

Answer 2

Question 3

whats the difference of 2-deoxyribose vs ribose ? Whats different in the 2’ deoxy ? Which one is more stable and why ?

Answer 3

Question 4

What are purines vs pyrimidines, ? What does the bottom nitron in 5’ member ring connect to ? Are bases charged ?

Answer 4

Question 5

What do the bases provide ?

Answer 5

Question 6

What is the purpose of a negetive charge ? The sugars and phosphate serve what purpose ?

Answer 6

Question 7

What two forces help the bases stay togethere ?

Answer 7

van der waals and hydrophobic effect .

Question 8

What is the A form of DNA versus the B form and Z form,

explain right twist vs left twist, and which leaves a zig zag

Answer 8

Question 9

What does supercoiling do ?

Answer 9

Question 10

Go to the order at which chromatin are organized .

Answer 10

Question 11

What are the four tpes of rRNA molecules in Eukarotic cells ?

How about the three in prok

Which organell has simialr ribosome to prok ?

Answer 11

Question 12

What is ment by the T and D and Pseudouridine in a tRNA ?

Answer 12

Question 13

Whhat are the three mechanism of dna replication ?

Answer 13

Question 14

What are the rules of replication ?

Answer 14

Question 15

How many origin site does prok and euk and yeast have ?

Answer 15

Question 16

Do the anti parallel strands replicate simultenuously ? is the leading strand and lagging strands 5’-3’ ?

Answer 16

Question 17

What is 3’-5’ exonuclease ? what are some proof reading activities ? In DNA replication, what is added to the free 3’ OH group ? What is the use of a primer ?

What is the role of DNA pol 1,2,3 ?

Answer 17

Question 18

in Eukaryotic DNA polymease, that is the fuction of A, B and Y , D

which oen makes primase ?

who does pol D work in conjunction with ?

Answer 18

Question 19

What is the role of helicase ? Single strand binding protein ?

Answer 19

Question 20

What is the role of topoisomerase ?

What i the fuction of the 1 and 2 DNA topoisomerase ?

Answer 20

Question 21

What is the role of RNA primers, and primase ?

Answer 21

Question 22

What is the role of DNA polymease ? What direction does it synthesize ?

Answer 22

Question 23

What is the role of the replication folk ? How is maintained ?

Read the paragrapth

Answer 23

Question 24

What is the role of DNA ligase ? What direction ?

Answer 24

Question 25

Overview of the eukroitic replication complex

Answer 25

Question 26

What are telomeres ? What is a problem developed in the lagging stand , what does it result ?

Answer 26

Question 27

What is the role of telomerase ? Where does the primase bind ? What does telomere consist of in terms of bases ? What does telomerase contain and what does it act like ?Where are telomerase kept active ? Why is it important that telomerase is in reproductive cells ?

Answer 27

Question 28

What is the connection between cancer and telemorase ? What is a way to detect cancer ? What is the problem if telemorase was shut off ?

Answer 28

Question 29

What is the association between telomere and aging ?

Answer 29

Question 30

What are some examples of DNA damage that be based by mutagens ( list of mutagens)

Answer 30

Question 31

What is a spontaneous mutations ? What is tautomerism,Depurination,Deamination,Transition,Transversion ?

Answer 31

Question 32

What is induced mutatation ? What is one of them ?

Answer 32

Question 33

What is base excision repair ?

Answer 33

Question 34

What is nucleotide excision repair ?

Answer 34

Question 35

What is mistched repair ?

Answer 35

The stand that is methylaton has the GATC sequnce, then MUT S finds the sequence(correct strand) that is damaged, and then MuT L binds, Then the Mut H binds to the CATC ( highly methylated site) ​ Then the MUt S and L interact with MUt H by lopping , which Mut H makes a hashes( cuts) and cuts the unmethylated, and endoclease cuts past the mismath strand where the Mut S and L are, and RNA poly is used

Question 36

What is transcription coupled repair ?

Answer 36

Question 37

What is Xeroderma pigmentosum ? What is it fuciton ?

Answer 37

Question 38

What are the three types of recombination ? What ar ethe consequences of the dynamic nature of chromosome ?

Answer 38

Question 39

What is homologous recombination ? What is holliday model ?

Answer 39

Question 40

What is translocation ?

Answer 40

Question 41

What is transposable elements ?

Answer 41

Question 42

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Question 43

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Question 44

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Question 45

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Question 46

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Question 47

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