digestive tract histology Flashcards

(50 cards)

1
Q

esophagus: epithelia type?

A

nonkeratinized stratified squamous epithelium

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2
Q

esophagus: upper 1/3 exists of?

A

striated muscle

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3
Q

esophagus: middle and lower 1/3 exists of?

A

smooth muscle

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4
Q

where in the esophagus striated muscle?

A

upper 1/3

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5
Q

where in the esophagus smooth muscle?

A

lower 1/3

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6
Q

nonkeratinized stratified squamous epithelium

which part of digestive tract?

A

esophagus

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7
Q

stomach: wat color are parietal cells in histology?

A

pink (eosinophilic)

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8
Q

stomach: what color are chief cells in histology?

A

dark purple red (basophilic)

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9
Q

stomach: what type of exocrine cells?

A

parietal cells: secrete gastic acid
chief cells: secrete pepsinogen (inactive form; cleaves proteins)

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10
Q

parietal cells: role?

A

secrete gastric acid

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11
Q

which cells in stomach secrete gastric acid?

A

parietal cells

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12
Q

chief cells: role?

A

secrete pepsinogen

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13
Q

which cells in stomach secrete pepsinogen?

A

chief cells

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14
Q

chief cells: where in stomach?

A

at the base of glands
in fundus and corpus

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15
Q

what does pepsinogen do?

A

inactive form of pepsin

digests proteins

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16
Q

what does the duodenum have to increase the absorptive surface?

A

villi and microvilli

plicae circulares

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17
Q

villi and microvilli: role?

A

increase absorptive surface

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18
Q

what kind of glands in duodenum?

A

Brunner glands

secrete bicarbonate

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19
Q

what do Brunner glands do?

A

secretes bicarbonate

protects the mucosa from acidic stomach contents

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20
Q

where are the Brunner glands located?

A

in the submucosa of the duodenum

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21
Q

what kind of crypts in duodenum?

A

crypts of Lieberkuhn

22
Q

what is the role of the crypts of Lieberkuhn?

A

contain stem cells

replace enterocytes, goblet cells, Paneth cells

23
Q

what do Paneth cells secrete?

A

antimicrobial compounds: defensins, lysozyme, TNF

24
Q

which cells in the duodenum secrete antimicrobial compounds?

25
which cells in the duodenum play a role in the innate immune system?
Paneth cells
26
what can you find in the distal duodenum? (anatomically)
plicae circulares
27
plicae circulares: where in duodenum?
distal duodenum everywhere in digestive tract except in first portion of the digestive tract
28
plicae circulares: function?
increase surface area spiral/circular folds in the digestive tract
29
jejunum: histology?
villi, crypts of Lieberkuhn
30
what kind of crypts in jejunum?
lieberkuhn
31
how are the plicae circulares different in the jejenum compared to the ileum?
more numerous and taller (more prominent)
32
where are plicae circulares more prominent?
jejunum
33
jejunum: appearance on CT with oral contrast?
feathered
34
which part of the gut has a feathered appearance on CT with oral contrast?
jejunum
35
duodenum: histology?
villi and microvilli, Brunner glands, crypts of lieberkuhn, plicae circulares
36
ileum: histology?
villi, Peyer patches, crypts of lieberkuhn, plicae circulares largest number of goblet cells
37
goblet cells: role?
secrete mucus
38
where are the largest number of goblet cells in the gut?
ileum
39
where can you find crypts of lieberkuhn?
between villi of the small intestine (duodenum, jejunum, ilieum) also in colon
40
where can you find villi (and microvilli) in the gut?
duodenum, jejunum, ileum not in colon
41
where are Peyer patches?
ileum
42
what are Peyer patches?
submucosal lymphoid follicles contain M cells
43
Role of M cells in Peyer patches?
transport antigens to underlying lymphoid follicles -> start immune response
44
villi, peyer patches, plicae circulares, crypts of lieberkuhn. where?
ileum
45
villi, crypts of lieberkuhn, prominent plicae circulares where?
jejunum
46
villi, Bunner glands, crypts of lieberkuhn, plicae circulares where?
duodenum
47
colon: are there villi?
no
48
colon: histology?
crypts of lieberkuhn, abundant goblet cells no villi
49
where are goblet cells abundant?
colon
50
which part of the intestine has no villi?
colon