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Drug profiles > Diphenhydramine (Benadryl) > Flashcards

Diphenhydramine (Benadryl) Flashcards

1
Q

Pharmacology and Actions

A
  • Histamine H1 receptor antagonist of effector cells respiratory tract, blood vessels, and GI smooth muscle
  • Has anticholinergic actions, making it useful in treating and preventing acute dystonic reactions to antipsychotic drugs.
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2
Q

Indications

A
  • Treatment of allergic reactions
  • Treatment and prevention of acute dystonic reactions from antipsychotic drugs
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3
Q

Absolute Contraindications

A
  • hypersensitivity
  • newborns
  • allergy
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4
Q

Precautions and Side Effects

A
  • usually causes sedation, but can paradoxically cause excitation in children
  • has additive sedation effects if combined with alcohol or other CNS depressants
  • can cause hypotension when given IV/IO
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5
Q

Administration (route, onset, peak, duration, dose)

A

-IV/IO
-Onset 10-15min
-Peak 1hr
-Duration 6-8hrs
-Dose 1mg/kg Max50mg

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Drug profiles (9 decks)

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