Diseases of salivary glands- Benign

Question 1

Distributions of salivary gland tumors- label the percentages that the tumor presence in these major salivary glands; is it benign or malignant?

1. parotid
2. submandibular
3. sublingual

Answer 1

Parotid: 50% 50%

Submandibular: 40% B; 60% M

Sublingual: 20%B; 80% M

Question 2

List in order from least to greater risk for a tumor to be malignant in the following glands:

• Submandibular
• Parotid
• Sublingual

Answer 2

Parotid, Submandibular, Sublingual

Sublingual is LETHAL

Question 3

Distributions of salivary gland tumors- label the percentages that the tumor presence in these minor salivary glands is it benign or malignant?

1. Palate
2. Buccal mucosa
3. Upper labial mucosa
4. Lower labial mucosa
5. Tongue
6. Floor of mouth
7. Retromolar pad

Answer 3

1. Palate: 50-50
2. Buccal mucosa: 50-50
3. Upper labial mucosa: 80B- 20M
4. Lower labial mucosa: 15B- 85M
5. Tongue: up to 90
6. Floor of mouth: up to 90
7. Retromolar pad: up to 90

Question 4

Describe a benign neoplasm:

Answer 4

• slow growth
• movable
• asymptomatic
• intact mucosa

Question 5

Describe a malignant neoplasm:

Answer 5

• rapid growth
• fixed
• symptomatic
• ulcerated

Question 6

List the benign salivary gland tumors: (5)

Answer 6

1. benign mixed tumor (pleomorphic adenoma)
2. monomorphic adenoma
3. Warthin’s tumor (papillary cystadenoma lymphomatosum)
4. Oncocytoma
5. ductal papillomas

BMWOD

Question 7

• most common salivary gland neoplasm
• middle-aged females
• painless slowly growing mass

Answer 7

Pleomorphic adenoma

Question 8

Patient presents with this painless mass. States that it appeared awhile ago and hasn’t grown much over time. It appears an enlarged tumor of the parotid gland.. Diagnose this:

Answer 8

pleomorphic adenoma

Question 9

Patient presents with this enlarged tumor of the palate. She is a middle-aged female and states that this is painless just annoying as it has been like this for a few years. The hole seen in the image is a biopsy site. Diagnose this:

Answer 9

pleomorphic adenoma

Question 10

Pt presents with a tumor of the upper lip. She is middle-aged and states this is painless and has been slow growing… Diagnose:

Answer 10

Pleopmorphic adenoma

Question 11

The most common type of salivary gland tumor encountered that can be seen in a variety of locations:

Answer 11

pleomorphic adenoma

Question 12

What tumor presents histologically with:

• variable histology
• mixture of ductal and myoepithelial elements
• encapsulated

Answer 12

Pleomorphic adenoma

Question 13

Patient presents with a salivary gland tumor. States that it is painless and has been around for months. Upon biopsy you note that it is a mixture of ductal and myoepithelial elements and is also encapsulated. Diagnose this:

Answer 13

pleomorphic adenoma

Question 14

Your pleomorphic adenoma an have some cool histology, this includes:

Answer 14

ability to make cartilage or bone

Question 15

• upper lip
• middle-aged females
• painless slow growing mass
• benign

Answer 15

monomorphic adenoma

Question 16

Benign salivary gland tumor most likely to be encountered in the upper lip:

Answer 16

monomorphic adenoma

Question 17

Middle aged female patient presents with slow growing mass on the upper lip. She states that she is not in pain. Diagnose this:

Answer 17

monomorphic adenoma

MONOMORPHIC ADENOMA: MOstly in upper lip

Question 18

What tumor presents histologically with:

• uniform pattern
• single layer cords of columnar or cuboidal epithelium
• may demonstrate papillary projections
• loose connective tissue stroma with prominent vascularity
• thin fibrous capsule

Answer 18

monomorphic adenoma

Question 19

This image shows the ENTIRE histological slide looking the exact same. Notice the loos connective tissue stroma with prominent vascularity.

Answer 19

Monomorphic adenoma

Question 20

Patient presents and says that they have been diagnosed with Warthin’s Tumor. What is another name for this?

Answer 20

Papillary cystadenoma lymphomatosum

Question 21

• 2nd most common benign salivary gland neoplasm
• occurs MOSTLY in the parotid gland
• Appears bilaterally
• Middle-aged males (lower in black)
• Smoking
• Painless slow growing nodular mass

Answer 21

papillary cystadenoma lymphomatosum

Question 22

Male white patient presents with a slow growing mass, and you notice its location is on the parotid gland and its bilateral growth. You notice the smell of smoke on the patient:

Answer 22

Papillary cystadenoma lymphomatosum

Question 23

What tumor presents histologically with:

• oncocytic ductal epithelium (uniform double rows)
• lymphoid aggregate
• papillary cystic configuration

Answer 23

papillary cystadenoma lymphomatosum

Question 24

You take a biopsy of a parotid gland tumor and notice these uniform double rows of these oncocytic cells that appear to be lining the cystic spaces. What might be a potential diagnosis?

Answer 24

papillary cystadenoma lymphomatosum

Question 25

• rare benign salivary gland neoplasm
• females 8th decade
• majority of these tumors affect the parotid gland
• large epithelial cells, oncocytes
• painless, slow growing mass
• MULTIFOCAL

Answer 25

oncocytoma

Question 26

Benign multifocal tumor of the parotid gland seen in 80 year old female:

Answer 26

oncocytoma

Question 27

What tumor presents histologically with:

• large polyhedral cells abundant in granular eosinophilic cytoplasm (due to mitochondria)
• limited stoma (thin fibrovascular septa)
• lymphoid infiltrate

Answer 27

Oncocytoma