DNA Flashcards
(25 cards)
What is the full name of DNA
Deoxyribonucleic acid
What shape is DNA?
Double helix
What’s the structure of the DNA helix?
2 nitrogen bases bond together to make the steps of the helix; sugar and phosphate chains make up the sugar phosphate backbone which provides structural support
What is semi conservative?
The new DNA strand contains one strand that is old and one that is new.
What is a nucleotide?
They are the monomers of Nucleic acid that makes up DNA. It is made up of sugar, a phosphate and a nitrogenous base.
What are the four nitrogenous bases?
Adenine
Guanine
Thymine
Cytosine
What bond is between the two bases of a DNA molecule?
Hydrogen bases
What is DNA helicase?
An enzyme that unwinds the double helix during DNA replication.
What is DNA polymerase?
An enzyme involved in DNA replication that joins individual nucleotides by forming phosphodiester bonds to produce a DNA molecule and the phosphate sugar backbone of the DNA.
What is a mutation?
An error that occurs during DNA replication.
Who is Watson and crick?
Developed the 3D double helix model of DNA
Which bases are pyrimidines?
Thymine
Cytosine
Which bases are purines?
Guanine
Adenine
How want rings do purines have?
Double ring
How many rings do pyrimidines have?
1
Describe the process of DNA packing?
- DNA is wrapped around histones - protein beads
- DNA is condensed into a helix (30nm fibre)
- DNA is looped around a protein core (300nm fibre)
Which is the base in RNA that isnt in DNA?
Uracil
Which base group is uracil in?
Pyrimidines
What are the differences between DNA and RNA?
- in RNA there is no thymine. Thymine is replaced by uracil.
- deoxyribose is replaced by ribose in RNA
- RNA is shorter, DNA is loner
- RNA is single stranded, DNA is double stranded
What are ribosomes made up of?
- proteins
- rRNA
What do you need for DNA replication?
- Nucleotides
- containing deoxyribose sugar
- phosphate
- nitrogen containing base - Enzymes
- to join nucleotide together
- to unwind the helix
- to carry out proof reading - Chemical energy
- ATP to power the reactions
Explain the process of DNA replication.
- The original DNA molecule unwinds due to the enzyme DNA helicase
- DNA helicase causes the 2 strands of DNA to separate
- Free nucleotides in the nucleoplasm are attracted to their complementary base pairs.
- The strong phosphate sugar backbone is rejoined by DNA polymerase forming 2 identical strands of DNA because the strands each contain half of the original material it is called the semi conservative method of replication
What’s the replication fork?
Very active area where DNA replication takes place