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Microbiology > DNA Virus > Flashcards

DNA Virus Flashcards

(96 cards)

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1
Q

Naked icosahedral

Single-stranded linear DNA virus

A

Parvovirus

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2
Q

ERYTHEMA INFECTIOSUM (FIFTH DISEASE)

A

Parvovirus

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3
Q

APLASTIC CRISIS

A

Parvo Virus

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4
Q

 Second trimester: Hydrops Fetalis

A

Parvo Virus

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5
Q

can be used with aplastic crisis

A

IVIG

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6
Q

acute hemorrhagic cystitis

A

Adenovirus

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7
Q

Cowdry type B intranuclear basophilic inclusion bodies

A

Adenovirus

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8
Q

Naked icosahedral

Double-stranded circular DNA

A

HPV

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9
Q

Naked icosahedral

Double-stranded circular DNA

A

Papovaviridae

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10
Q
  • Infect squamous cells and induce formation of cytoplasmic vacuole (koilocytes)
A

HPV

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11
Q

verruca vulgaris

A

HPV 1,2,3,4

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12
Q

Genital warts (condyloma acuminata

A

HPV 6,11

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13
Q

Most common viral STD

A

HPV Condyloma Acuminata HPV 6,11

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14
Q

Carcinoma of the cervix, vulva, penis, anus

A

HPV 16,18,31,33

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15
Q

Genital warts DOC

A

Podophylin

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16
Q

Skin warts DOC

A

Liquid Nitrogen

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17
Q

Plantar Warts DOC

A

Salicylic acid

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18
Q

small, round, deeply basophilic nuclei surrounded by a clear

halo and pale-staining cytoplasm

A

Koilocytes - HPV

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19
Q

progressive multifocal leukoencephalopathy in patients with AIDS

A

JC Polyoma v.

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20
Q

 Demyelinating disease that affects the oligodendrocytes characterized by deficits in speech, coordination, and memory

A

rogressive multifocal leukoencephalopathy -> JC Polyoma v

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21
Q

hemorrhagic cystitis and nephropathy in patients with solid organ (kidney) and bone marrow transplants

A

BK Polyoma v. (BK - Bladder and Kidney)

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22
Q

Decoy cells

A

Bk Polyoma

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23
Q

HSV 1 Transmission

A

Saliva/ Direct

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24
Q

HSV 2 Transmission

A

Sexually transmitted

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25
TORCH
HSV 2 - Neonatal Hepres
26
Temporal lobe encephalitis
HSV 1
27
Site of Latency HSV 1
Trigeminal Ganglia
28
Site of Latency HSV 2
Lumbosacral Ganglia
29
HSV Tszanck
Tzanck smear: multinucleated giant cells
30
Cowdry Type A: | Cowdry Type B:
Type A: HSV, VZV | Type B: Adeno
31
DOC HSV
Acyclovir - only shortens duration and decreases shedding
32
the most common cause of sporadic, fatal encephalitis in the USA
HSV 1
33
VZV Latent site
Dorsal root ganglia
34
dewdrop on a rose petal appearance’
VZV
35
begins on trunk; spreads to face and extremities (centrifugal)
Varicella
36
Complications Varicella
 Complications: Pneumonia, Encephalitis, Reye’s syndrome (Asrpirin also)
37
most common complication of Herpes Zoster/ Shingles
Poestherpitic neuralgia
38
 Reactivation of latent VZV residing within geniculate ganglion
Ramsay Hunt/ Herpes Zoster Oticus
39
Ramsay Hubt Triad
ipsilateral facial paralysis, ear pain, and vesicles on the face
40
Cicatrix
Congenital Varicella - 6-12 weeks AOG
41
Varicella DOC
Given within 24 hours to severe cases only
42
Ramsay Hunt
Valcyclovir + Prednisone
43
Active Varicella Vaccine
given within 5 days
44
Anti VZV Ig
96 h after exposure
45
o Impair assembly of the MHC class 1-viral peptide complexes
Immediate early proteins of CMV
46
 Most common infectious cause of congenital abnormalities
CMV
47
 Most common intrauterine viral infection
CMV
48
CMV Most common when the mother is infected
1st Trimester
49
HETEROPHIL-NEGATIVE MONONUCLEOSIS
CMV
50
 AIDS retinitis
CMV
51
Giant cells with owl’s-eye nuclear inclusion
CMV
52
DOC CMV
Gangcylovir
53
DOC for prevention of CMV disease in solid-organ transplant patients is
Valgancyclovir
54
Lymphoid and B lymphocytes tgrough CD21
EBV
55
INFECTIOUS MONONUCLEOSIS
Eeeeepstein Bar EEEnfectious Mono
56
Kissing disease’
Epstein Bar
57
Heterophil Positive Mononucleosis
EBV
58
Rare complication of Infectious Mono
splenic rupture is a rare complication (Avoid contact sports!)
59
EBV Malignancies
Burkitt's lymphoma - Africans <3 Nasopharyngeal CA - Chinese Hairy Leukoplakia - AIDs
60
elevated “atypical lymphocytes”  Downey cells
EBV
61
Use of this antibipotic in mononucleosis can cause characteristic maculopapular rash
Amoxicillin
62
- rose-colored macules appear on body after several days of high fever; can present with febrile seizures; usually affects infants
Roseola/ HHV 6
63
erythematous papules on soft palate and base of the UVULA
Nagayama Spots - HHV6
64
 most common AIDS-related malignancy
Kaposi Sarcoma - HHV 8
65
Kaposi Sarcoma - HHV 8 Tx
Surgical excision | Radiation
66
Largest DNA Virus
Pox Virus
67
Variola Virus
Small Pox
68
Brick-shaped poxvirus
Variola
69
 Lesions with same stage of development
Variola - Small Pox (Compare to chicken pox -> with different stages)
70
lesions may become umbilicated or confluent
Small Pox
71
Cenntrifugal rash
Small Pox, Chicken Pox
72
Beau's Lines
Kawasaki Disease
73
Centripetal
Rocky Mountain Spotty Fever
74
Guarnieri Bodies
Small Pox
75
 flesh-colored dome-shaped papules with central umbilication
Moluscum contagiosum
76
Henderson-Patterson bodies:
Moluscum Contagiosum
77
Moluscum Contagiosum DOC
Cifodovir
78
DOC Smallpox
Tecovirimat
79
incomplete circular double-stranded DNA
Hepa B
80
- the only DNA virus that produces DNA by reverse transcription with mRNA as the template; not a retrovirus but has reverse transcriptase
Hepa B
81
- hepatocellular injury due to immune attack by cytotoxic T cells  HBV has no cytopathic effect
Hepa B
82
used as marker of potential infectivity
HBeAg
83
Extrahepatic Manifestations of Hepa B
Aplastic Anemia MPGN Polyarteritis Nodosa
84
eosinophilic globule of cells that represents a dying hepatocyte often surrounded by normal parenchyma
Councilman Body - Hepa B
85
Granular eosinophilic “ground glass” appearance IN Liver Biopsy
Hep B
86
HBsAg, IgM anti-HBc
Acute Infection
87
HBsAg, IgG anti-HBc
Chronic Infection
88
HBeAg, HBV DNA
Markers of Replication
89
DOC Hepa B
``` LATE Lamivudine Alpha Interferon Tenofovir Entecavir ```
90
HBsAg, HbeAg
Incubation Period
91
HBsAg, HbeAg, IgM
Acute Infection
92
Only IgM positive
Window
93
Anti HBs, IgG
Complete Recovery
94
HBsAg, IgG
Chronic Carrier
95
HBsAg, IgG, HbeAg
Chronic Active
96
Anti HBs Only
Vaccinated

Microbiology (7 decks)

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