Donovanosis

Question 1

Donovanosis organism & Clin features

Answer 1

AKA granuloma inguinale

Kleb granulomatis

Painless, slow ulcers with retinal nodes & pseudobuboes (subcutaneous granulomas)

Question 2

Donovanosis Ix & Tx

Answer 2

Difficult to culture & NO NAATs

Crush biopsy - dark stained Donovan bodies

First line:
azithro 1g weekly for 3 weeks

Second line:
Doxy or Ery or Septein