Dosages

Question 1

Endometritis tx (no GBS colonization)

Answer 1

Clindamycin 900 mg every 8 hours plus
Gentamicin 5 mg/kg every 24 hours (preferred) or 1.5 mg/kg every 8 hours (without a loading dose)*

Question 2

Endometritis tx (with GBS colonization)

Answer 2

Clindamycin 900 mg every 8 hours plus
Gentamicin 5 mg/kg every 24 hours (preferred) or 1.5 mg/kg every 8 hours (without a loading dose) plus
Ampicillin 2 g IV every 6 hours or
Ampicillin-sulbactam 3 g IV every 6 hours

Question 3

Chorio Abx for mild penicillin allx

Answer 3

Cefazolin 2 g IV every 8 hours

Gentamicin 2 mg/kg IV load followed by 1.5 mg/kg every 8 hours
or
5 mg/kg every 24 hours

Question 4

Chorio abx severe PCN allx

Answer 4

Clinda 900 mg IV every 8 hours
OR
Vanc 1 g IV every 12 hours

AND
Gent 2 mg/kg IV load followed by 1.5 mg/kg every 8 hours
or
5 mg/kg every 24 hours

Question 5

Chorio abx - no allx

Answer 5

Amp 2 g IV every 6 hours

And
Gent 2 mg/kg IV load followed by 1.5 mg/kg every 8 hours
or
5 mg/kg every 24 hours