Dose Flashcards
(9 cards)
The concentration of a drug vs effect of that drug on the body is known as?
drug response relationship
What is the onset of action
Time from administration to minimum effective concentration
What is the duration of action
The start of the minimum effective concentration to the end of the minimum effective concentration
What is the termination of action?
End of the minimum effective concentration to drug elimination
Explain first order kinetics?
The rate of elimination is proportional to the concentration gradient of the drug and dependent on the plasma concentration
Explain zero order kinetics?
The elimination of the drug is independent of the plasma concentration
What is a loading dose?
Initial amount of a drug required to fill the plasma to the desired drug concentration
What is steady state?
Absorption fo the drug is in equilibrium with its elimination
What is a maintenance dose?
The amount needed to reach the concentration to maintain therapeutic effect
