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Drug classes Flashcards

(86 cards)

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1
Q

what are the three types of nitrates?

A

nitroglycerine
ISDN
ISMN

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2
Q

-lol, -olol

A

beta blockers

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3
Q

-pine

A

calcium channel blockers (DHP)

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4
Q

ranolazine

A

sodium channel blocker

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5
Q

what are the two groups in the calcium channel blockers class?

A

DHP
NDHP

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6
Q

name the CCB NDHPs

A

verapamil
diltiazem

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7
Q

-pril

A

ACEI

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8
Q

-sartan

A

ARB

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9
Q

name the ARNI drug

A

sacubitril / valsartan

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10
Q

name the osmotic diuretic

A

mannitol

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11
Q

name the carbonic anhydrase inhibitor

A

acetazolamide

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12
Q

-mide

A

loop diuretics

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13
Q

-thiazide

A

thiazides

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14
Q

what are aldosterone receptor antagonists also known as?

A

K-sparing diuretics

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15
Q

name 2 aldosterone receptor antagonists

A

spironolactone
eplerenone

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16
Q

-none

A

K-sparing diuretics
(ARA)

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17
Q

name two balanced veno/vaso dilation combos

A

hydralazine + nitrate
sodium nitroprusside

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18
Q

name the CCB good for heart failure

A

amlodipine

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19
Q

which loop diuretic can cause the worse toxicity and what toxicity is it?

A

ethacrynic acid
ototoxic

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20
Q

3 thiazides used to treat hypertension that don’t follow the name game

A

indapamide
metolazone
chlorthalidone

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21
Q

2 K sparing diuretics used treat hypertension that don’t follow the name game

A

triamterene
amiloride

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22
Q

aliskiren

A

renin inhibitor

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23
Q

renin inhibitor used to treat hypertension

A

aliskiren

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24
Q

direct arterial vasodilators used to treat hypertensive emergencies

A

Na Nitroprusside
diazoxide
labetalol

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25
-sin
alpha receptor blockers
26
-dine
central alpha 2 agonists
27
name the central alpha 2 agonists used to treat hypertension but doesn't follow the name game
methyldopa
28
anti-arrhythmic drugs in class IA
Double - disopyramide Quarter - quinidine Pounder - procainamide
29
anti-arrhythmic drugs in class IB
Lettuce - lidocaine Tomato - tocainide Mayo - mexiletine
30
anti-arrhythmic drugs in class IC
Fries - flecainide Please - propafenone
31
anti-arrhythmic drugs in class II
Eat - esmolol More - metoprolol Poor people (food) - propanolol
32
anti-arrhythmic drugs in class III
Ami - amiodarone Says - satolol Drones - dronedarone Don't - dofetillide Interest - ibutillide Bret - bretylium
33
anti-arrhythmic drugs in class IV
D and V dilitiazem verapamil
34
AAD used for PSVT
adenosine
35
AAD that increases vagal tone, causes bradycardia and has a low TI
digoxin
36
AAD that treats bradycardia
atropine
37
AAD that is bossy and regulates ions Na+, K+, and Ca++
magnesium
38
antithrombotic class that inhibits the cross-link between fibrinogen and platelets
Gp 2b/3a inhibitors
39
-grel
ADP/P2Y12 receptor antagonists
40
what do ADP/P2Y12 receptor antagonists do?
inhibit ADP and P2Y12 binding = inhibits Gp 2b/3a formation
41
what shouldn't clopidogrel be used with?
Prilosec
42
what drug does Clopidogrel have a synergistic effect with?
ASA
43
a drug that belongs to the ADP/P2Y12 class but does not follow the name game
Ticlopidine
44
COX-1 Inhibitor
Aspirin (ASA)
45
what class are the nonselective reversible inhibitors of COX-1 and COX-2?
NSAIDS
46
what drug should not be given before aspirin?
NSAID
47
drug class that allows cAMP to increase, increases contractility, and therefore decreases platelet aggregation
PDI
48
2 drugs in the PDI class
Crazy - cilostazol Dude - dipyridamole
49
what can be given with dipyridamole?
warfarin
50
what are 2 drug classes that are direct acting anticoagulants?
heparin LMWH
51
an indirect acting anticoagulant that is a vitamin K antagonist
warfarin
52
antidote for heparin and LMWH
protamine
53
which clotting factors does warfarin inactivate?
2, 7, 9 and 10
54
what is the antidote for warfarin?
phytonadione
55
-ban
non-vitamin K antagonists
56
drug class that directly inhibits factor Xa
Non-vitamin K antagonists
57
a drug that is a non-vitamin K antagonist but does not follow the name game
dabigatran
58
-plase
TPA inhibitors
59
what are TPA inhibitors main job?
fibrinolytic - lyse existing clots
60
what can TPA inhibitors be reversed by?
alpha 2 antiplasmin T/A acids RBCs/blood
61
HMG-CoA reductase inhibitor
statins
62
what does HMG-CoA reductase do?
makes cholesterol in the liver
63
what are statins metabolized by?
CYP3A4
64
what shouldn't a patient drink while on a statin?
grape fruit juice
65
cholesterol absorption inhibitor
ezetimibe
66
where do cholesterol absorption inhibitors work?
instestine
67
what can ezetimibe be used with?
statin
68
if ezetimibe and statin are used together, what should be monitored?
ALT, AST
69
what is the MOA for bile acid binding resins?
binds resins to bile acids, which leads to increased cholesterol being converted to bile acids
70
what can a bile acid binding resin be combined with for a better response?
statin
71
name the 3 bile acid binding resins
colestipol colesevelam cholestyramine
72
3 drugs/class that treat hypertriglyceridemia
fibrates niacin omega-3 fatty acids
73
which drugs are used to treat hypertriglyceridemia in patients with DM2?
fibrates
74
niacin ADR
flushing itching
75
-mab
PCSK9 inhibitors
76
inhibited by monoclonal antibodies
PCSK9
77
PCSK9 ADR
URI flu-like myalgia ISR
78
a drug related to PCSK9 inhibitors that wants to be included
Inclisiran
79
what is Inclisiran used for?
familial hypercholesterolemia ASCVD
80
drug class that inhibits ATP-citrate lyase
ACL-inhibitors
81
ACL-inhibitor
being pedo gives me the IC Bempedoic acid
82
bempedoic acid ADR
urIC acid gout achilles tendon rupture
83
2 OTC omega-3 fatty acids
EPA DHA
84
2 rx omega-3 fatty acids
ethyl esters icosapent ethyl
85
which omega 3 fatty acid is used for adults with TG over 500
icosapent ethyl
86
omega-3 fatty acid ADR
atrial fibrillation atrial flutter

Pharmacology (13 decks)

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