Drug development workshop Flashcards

1
Q

explain the link between EGFR and head and neck cancer

A

EGF receptor acitvates cyclin D and other pathways which result in cell proliferation

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2
Q

phosphorylation can switch protein activity on or off mainly?

A

on

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3
Q

what are the 2 forms of entry for covid into a human cell?

A

direct fusion
endosomal

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4
Q

direct fusion -> entry of covid into a human cell

Cleavage of ?? by ?

Binding to ? receptor

Processing by ?

Diffusion

A

spike protein
Furin

ACE2

TMPRSS2

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5
Q
A
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