Drugs 1:1-22

Question 1

propranolol brand name and uses

Answer 1

• Inderal LA / XL

- HTN

Question 2

propranolol dosing

Answer 2

80 - 160 mg daily

Question 3

atenolol brand name and uses

Answer 3

• Tenormin
• chronic angina
• HTN

Question 4

atenolol dosing

Answer 4

• chronic angina: 50 - 200 mg daily

- HTN: 50 - 100 mg daily; target regimen 100 mg daily

Question 5

atenolol / chlorthalidone brand name and uses

Answer 5

• Tenoretic

- HTN

Question 6

atenolol / chlorthalidone dosing

Answer 6

50/25 - 100/25 mg daily

Question 7

metoprolol tartrate brand name and uses

Answer 7

• Lopressor
• chronic angina
• HTN

Question 8

metoprolol tartrate dosing

Answer 8

• 25 mg bid up to 200 mg bid

- target HTN regimen 50-100 mg bid

Question 9

metoprolol succinate brand name and uses

Answer 9

• Toprol XL
• chronic angina
• CHF
• HTN

Question 10

metoprolol succinate dosing

Answer 10

• chronic angina: 100 mg daily to 400 mg daily
• CHF: 12.5 mg daily to 200 mg daily; double the dose q2weeks to highest tolerated
• HTN: 25 - 100 mg daily to 400 mg daily

Question 11

ranolazine brand name and uses

Answer 11

• Ranexa

- chronic angina

Question 12

ranolazine dosing

Answer 12

• 500 mg bid

- may increase to 1000 bid based on symptoms

Question 13

bisoprolol brand name and uses

Answer 13

• Zebeta

- HTN

Question 14

bisoprolol dosing

Answer 14

• may start at 2.5 mg, 20 mg max

- 5 - 10 mg daily

Question 15

bisoprolol and HCTZ brand name and uses

Answer 15

• Ziac

- HTN

Question 16

bisoprolol and HCTZ dosing

Answer 16

• 2.5/6.25 - 20/12.5 mg daily

- 6.25 mg HCTZ per tablet

Question 17

nebivolol brand name and uses

Answer 17

• Bystolic

- HTN

Question 18

nebivolol dosing

Answer 18

• 5 -10 mg daily

- titrate at 2 wk intervals up to 40mg/day max

Question 19

carvedilol brand name and uses

Answer 19

• Coreg, Coreg SR
• CHF
• HTN

Question 20

carvedilol dosing

Answer 20

• Coreg CHF: 3.125 mg bid to 25 or 50 mg bid; titrate q2 weeks to highest tolerated; max by wt
• Coreg HTN: 6.25 mg bid to 25 mg bid; titrate q1-2 weeks
• Coreg SR CHF: 10 mg - 80 mg daily; titrate q1-2 weeks
• Coreg SR HTN: 20 mg - 80mg daily; titrate q1-2 weeks

Question 21

digoxin brand name and uses

Answer 21

• Lanoxin
• CHF
• atrial fibrillation and atrial flutter

Question 22

digoxin dosing

Answer 22

0.125 - 0.5 mg daily

Question 23

isosorbide dinitrate brand name and uses

Answer 23

• Isordil, Dilatrate-SR

- angina prophylaxis

Question 24

isosorbide dinitrate dosing

Answer 24

• Isordil: 5 - 40 mg tid; administer at 7-12-5 for nitrate-free interval
• Dilatrate-SR: 20 - 80 mg bid; administer at 8 and 2 for nitrate-free interval

Question 25

isosorbide mononitrate ER brand name and uses

Answer 25

- Imdur | - angina prophylaxis

Question 26

isosorbide mononitrate ER dosing

Answer 26

30 - 240 mg daily QAM

Question 27

nitroglycerin brand name and uses

Answer 27

- Nitrostat | - acute anginal pain

Question 28

nitroglycerin dosing

Answer 28

- q5 min prn (3 tabs/15 min, then 911) | - SIT DOWN; can use 5-10 min pre-activity

Question 29

hydralazine brand name and uses

Answer 29

- Apresoline | - HTN

Question 30

hydralazine dosing

Answer 30

20 - 200 mg split into 2-4 doses

Question 31

isosorbide dinitrate / hydralazine brand name and uses

Answer 31

- BiDil | - CHF

Question 32

isosorbide dinitrate / hydralazine dosing

Answer 32

- 20/37.5 mg tabs TID | - max 2 tabs tid

Question 33

clopidogrel brand name and uses

Answer 33

- Plavix - recent MI - CVA - established PVD

Question 34

clopidogrel dosing

Answer 34

75 mg daily

Question 35

prasugrel brand name and uses

Answer 35

- Effient | - acute coronary syndrome (ACS) with PCI

Question 36

prasugrel dosing

Answer 36

- 60 mg loading dose, 10 mg daily | - 5 mg daily maintenance if < 60 kg

Question 37

ticlodipine brand name and uses

Answer 37

- Ticlid | - CVA prevention

Question 38

ticlodipine dosing

Answer 38

250 mg bid

Question 39

ticagrelor brand name and uses

Answer 39

- Brilinta | - acute coronary syndrome (ACS) with PCI

Question 40

ticagrelor dosing

Answer 40

- 180 mg loading dose, 90 mg bid | - use with aspirin 75 - 100mg daily

Question 41

vorapaxar brand name and uses

Answer 41

- Zontivity - MI history - established PAD

Question 42

vorapaxar dosing

Answer 42

- 2.08 mg daily | - use with aspirin or clopidogrel

Question 43

dipyridamole brand name and uses

Answer 43

- Persantine | - with warfarin s/p cardiac valve replacement

Question 44

dipyridamole dosing

Answer 44

300 - 400 mg split into four doses