Drugs 2:26-51

Question 1

felodipine brand name and uses

Answer 1

• Plendil

- HTN

Question 2

felodipine dosing

Answer 2

2.5 - 10 mg

Question 3

amlodipine brand name and uses

Answer 3

• Norvasc
• HTN
• vasospastic / chronic stable angina

Question 4

amlodipine dosing

Answer 4

5 - 10 mg

Question 5

diltiazem brand name and uses

Answer 5

• Cardizem: angina prophylaxis
• Cardizem CD: HTN
• Tiazac: HTN

Question 6

diltiazem dosing

Answer 6

• Cardizem: angina prophylaxis: 30 - 120 mg tid
• Cardizem CD: HTN: 120 - 360 mg; target regimen = 360 mg daily
• Tiazac: HTN: 120 - 540 mg; target regimen = 360 mg daily

Question 7

verapamil brand name and uses

Answer 7

• Calan: HTN, vasospastic / chronic stable angina

- Isoptin SR: HTN

Question 8

verapamil dosing

Answer 8

• Calan: HTN: 120 - 360 split into 1-2x/day
• Calan: vasospastic / chronic stable angina: 120 - 480 mg split into 3x/day
• Isoptin SR: HTN: 120 - 360 split into 1-2x/day

Question 9

doxazosin brand name and uses

Answer 9

• Cardura XL
• BPH
• HTN

Question 10

doxazosin dosing

Answer 10

• BPH: 4 - 8 mg; titrate to 8 mg at 3-4 weeks if needed

- HTN: 1 - 16 mg; titrate q1-2weeks; retitrate if therapy interrupted

Question 11

terazosin brand name and uses

Answer 11

• Hytrin

- HTN

Question 12

terazosin dosing

Answer 12

• 1 - 20 mg split into 1-2x/day

- re-titrate if therapy interrupted several days

Question 13

clonidine brand name and uses

Answer 13

• Catapres / TTS

- HTN

Question 14

clonidine dosing

Answer 14

• Catapres: 0.1 - 0.8 mg split into 2x/day; max 2.4 mg;can increase 0.1-0.2 mg daily to response
• Catapres TTS: 0.1 - 0.3 mg wkly; max dose 0.6mg

Question 15

rosuvastatin brand name and uses

Answer 15

• Crestor

- antihyperlipidemic (Type IIa,IIb,IV)

Question 16

rosuvastatin dosing

Answer 16

5 - 40 mg; start 20 mg/day if LDL > 190; titrate q4-6 wks

Question 17

fluvastatin brand name and uses

Answer 17

• Lescol
• Lescol XL
• antihyperlipidemic (Type IIa,IIb)

Question 18

fluvastatin dosing

Answer 18

• Lescol: 20 - 80 mg split into 1-2x/day
• Lescol XL: 80 mg daily
• titrate q4-6wks

Question 19

atorvastatin brand name and uses

Answer 19

• Lipitor

- antihyperlipidemic (Type IIa,IIb,IV)

Question 20

atorvastatin dosing

Answer 20

• 10 - 80 mg

- titrate q4-6wks

Question 21

amlodipine / atorvastatin brand name and uses

Answer 21

• Caduet

- appropriate indications by agent

Question 22

amlodipine / atorvastatin dosing

Answer 22

2.5, 5, 10 mg amlodipine / 10, 20 , 40, 80 mg atorvastatin

Question 23

lovastatin brand name and uses

Answer 23

• Mevacor

- antihyperlipidemic (Type IIa,IIb)

Question 24

lovastatin dosing

Answer 24

• 20 - 80 mg

- titrate q4-6wks; dose with evening meal

Question 25

pravastatin brand name and uses

Answer 25

- Pravachol | - antihyperlipidemic (Type IIa,IIb)

Question 26

pravastatin dosing

Answer 26

- 10 - 80 mg | - titrate q4-6wks; dose with evening dosing

Question 27

simvastatin brand name and uses

Answer 27

- Zocor | - antihyperlipidemic (Type IIa,IIb,IV)

Question 28

simvastatin dosing

Answer 28

- 5 - 40 mg | - titrate q4-6wks; 80 mg/day dosage is restricted

Question 29

pitavastatin brand name and uses

Answer 29

- Livalo | - antihyperlipidemic (Type IIa,IIb)

Question 30

pitavastatin dosing

Answer 30

- 1 - 4 mg | - lower starting and maximum dosage if CrCl < 60

Question 31

gemfibrozil brand name and uses

Answer 31

- Lopid | - antihyperlipidemic (Type IV)

Question 32

gemfibrozil dosing

Answer 32

- 600 mg bid | - 30 minutes before morning and evening meals

Question 33

fenofibrate brand name and uses

Answer 33

- Tricor | - antihyperlipidemic (Type IIa,IIb,IV)

Question 34

fenofibrate dosing

Answer 34

- 48 or 145 mg daily | - 145 mg/day for LDL reduction; 48 mg/day if low CrCL

Question 35

fenofibric acid (choline) brand name and uses

Answer 35

- Trilipix | - antihyperlipidemic (Type IIa,IIb,IV)

Question 36

fenofibric acid (choline) dosing

Answer 36

- 45 or 135 mg daily | - 135 mg/day for LDL reduction; 45 mg/day if low CrCl

Question 37

cholestyramine powder brand name and uses

Answer 37

- Questran | - antihyperlipidemic (Type IIa)

Question 38

cholestyramine powder dosing

Answer 38

- 4 - 24 grams split into 1-2x/day | - titrate q4-6 wks

Question 39

colesevelam brand name and uses

Answer 39

- Welchol | - antihyperlipidemic (Type IIa)

Question 40

colesevelam dosing

Answer 40

6 tabs split into 1-2x/day

Question 41

niacin brand name and uses

Answer 41

- Niaspan | - antihyperlipidemic (Type IIa,IIb,IV)

Question 42

niacin dosing

Answer 42

- 500 - 2000 mg with snack | - qhs; titrate 500 mg q4wks to response

Question 43

ezetimibe brand name and uses

Answer 43

- Zetia | - antihyperlipidemic (Type IIa)

Question 44

ezetimibe dosing

Answer 44

10 mg daily

Question 45

ezetimibe / simvastatin brand name and uses

Answer 45

- Vytorin | - antihyperlipidemic (Type IIa)

Question 46

ezetimibe / simvastatin dosing

Answer 46

10/10 - 10/80 mg

Question 47

omega-3-acid ethyl esters brand name and uses

Answer 47

- Lovaza | - hypertriglyceridemia (> 500 mg/dL)

Question 48

omega-3-acid ethyl esters dosing

Answer 48

4 caps daily or 2 caps bid with food

Question 49

amiodarone brand name and uses

Answer 49

- Cordarone | - specific arrhythmias

Question 50

amiodarone dosing

Answer 50

200 - 400 mg split into 1-2x/day

Question 51

dronedarone brand name and uses

Answer 51

- Multaq | - atrial fibrillation

Question 52

dronedarone dosing

Answer 52

400 mg bid with food