Drugs affecting blood coagulatioon, platelet aggregation, fibrinolysis

Question 1

Maintain balance from bleeding and clotting

Answer 1

Haemostasis

Question 2

Vasoconstriction

Answer 2

Blood vessels, small and narrow restricting blood flow

Question 3

Clumping together of platelets can lead to

Answer 3

Thrombus (clot)

Question 4

Clot is broken down..

Answer 4

Fibrinolysis

Question 5

Coagulation

Answer 5

clotting

Question 6

Haemostasis, complex interaction between..

Answer 6

Blood vessels - vasoconstriction
Platelets
Coagulation - clotting factors and inhibitors
Fibrinolysis

Question 7

Fibrin framework

Answer 7

Protective mec, clotting stops access bleeds

Question 8

Venous thrombosis

Answer 8

Coagulation has major role

Some inherited/required

Question 9

Arterial thrombosis

Answer 9

Target platelet function

Coagulation and platelet drugs

Question 10

Thrombosis

Answer 10

Clot within a vessel

Question 11

Thrombosis is initiated by

Answer 11

pooling of blood in veins due to sluggish flow (bed rest, damaged vessels, atheromatous plaques)

Question 12

A clot that has become unattached to vessel wall and travelled through blood vessel causing blocks elsewhere

Answer 12

Embolus

Question 13

Embolus can block

Answer 13

Small blood vessels in pulmonary, cardiac, CNS circulation

Question 14

Successful in Venous Thrombosis ?

Answer 14

Modify coagulation

Question 15

Important in Arterial Thrombosis?

Answer 15

Modify platelet aggregation

Question 16

Modify clot, breakdown

Answer 16

after prophylaxis fails
prevent clot moving
prevent re-clotting