Drugs and Receptors

Question 1

Drugs which binds to Enzymes are..

Answer 1

Aspirin

Viagra

Question 2

Drugs which binds to Receptors are..

Answer 2

Salbutamol
B-Blockers
Anti Histamines

Question 3

Drugs which binds to Ion Channels are..

Answer 3

Local Anaesthetic

Benzodiazepine (Valium)

Question 4

Drugs which binds to Carrier Molecules are..

Answer 4

Omeprazole

Cocaine

Question 5

Drugs which binds to DNA are..

Answer 5

Hydrocortisone (steroids)

Question 6

Agonist

Answer 6

Bind to receptor causing a response, often mimic chemicals in body

Question 7

Antagonists

Answer 7

Binds to receptor and STOPS other chemicals from producing response

Question 8

2nd Messengers

Answer 8

cGMP, cAMP, Ca2+, IP3, DAG, NO

Question 9

What are the 5 cellular responses to drugs?

Answer 9

Contraction
Secretion
Excitation
Inhibition
Interruption of cell cycle

Question 10

What is Potency ?

Answer 10

Amount of dug required to produce a response to patient

Question 11

How do drugs work?

Answer 11

Bind onto receptors on cells to produce a response

Question 12

What is the lock and key mechanism?

Answer 12

A drug will only bind to specific target receptor

Question 13

What is the 2nd messenger in the relaxation of Smooth Muscle

Answer 13

cAMP

Question 14

What happens when a drug binds to receptor?

Answer 14

Causes activation of 2nd messenger > causes cascade of enzyme mediated reactions to happen causing a response