Drugs affecting GIT Motility - Week 5 Flashcards

1
Q

CTZ expand

A

Chemoreceptor Triggerone

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2
Q

CTZ Function

A

Mediates nausea & vomiting.

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3
Q

What makes CTZ effective in detecting emetic agents in systemic circulation & CSF?

A

Lack of BBB.

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4
Q

Nerve input of CTZ

A

Dopaminergic/tryptaminergic.

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5
Q

Vomiting centre function

A

Mediates olfactory, emotional, hormonal causes/triggers of nausea/vomiting.

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6
Q

What does the vomiting centre receive input from?

A

CTZ, GIT, CVS, limbic system.

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7
Q

Labyrinths via vestibular nuclei trigger

A

Nausea & vomiting associated w motion sickness.

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8
Q

Labryrinths via vestibular nuclei are under what nerve control?

A

Cholinergic/histaminergic nerve control.

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9
Q

Mechano/chemo-receptors GIT are under what nerve control?

A

Tryptaminergic nerve control.

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