Drugs from clinical cases- classification, mechanism, indications Flashcards Preview

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Flashcards in Drugs from clinical cases- classification, mechanism, indications Deck (23):
1

Aspirin

Salicylate.
Anti-platelet drug- inhibits COX-1.
Secondary prevention of thrombotic cerebrovascular/cardiovascular disease

2

Digoxin

Cardiac glycoside
Positive inotrope (increases cardiac contractility) and negative chronotrope
Heart failure, A. fib, atrial flutter

3

Amlodopine

Dihydropyridine calcium-channel blocker.
Reduces vascular tone; little effect on cardiac contractility.
Indicated in hypertension

4

Doxazosin

Alpha-blocker.
Vasodilator.
Resistant hypertension and benign prostatic hyperplasia.

5

Oxybutynin

Antimuscarinic.
Relaxes urinary smooth muscle.
Urinary incontinence.

6

Temazapam

Short-acting benzodiazapene.
Short term relief of anxiety; insomnia.

7

Ibuprofen

NSAID.
Inhibit cyclo-oxygenase.
Pain and inflammation.

8

Codeine

Weak opioid analgesic.
Mild to moderate pain.

9

Tramadol

Strong opiate analgesic
Moderate to severe pain.

10

Furosemide

Loop diuretic.
Inhibit reabsorption from the ascending limb of the loop of Henle.
Oedema (peripheral and pulmonary) due to heart failure resistant hypertension

11

Perindopril

ACE inhibitor.
Reduce angiotensin-II mediated vasoconstriction.
Heart failure, hypertension, diabetic nephropathy, ischaemic heart disease.

12

Amitriptylline

Tricyclic antidepressant.
Depression, diabetic neuropathy, neuropathic pain.

13

Tiotropium

Short-term antimuscarinic bronchodilator.
Breathlessness in COPD.

14

Salbutamol

Short-acting beta2-agonist.
Causes bronchodilatation.
Asthma; breathlessness in COPD

15

Alendronate

Bisphosphonate.
Inhibits bone resorption.
Osteoporosis; Paget's disease; hypercalcaemia

16

Bendroflumothiazide

Thiazide diuretic.
Inhibits sodium reabsorption at the DCT.
Mild -> moderate heart failure, oedema, hypertension

17

Diltiazem

Non-dihydropyridine calcium channel blocker.
Negative inotrope.
Prophylaxis/treatment of angina; hypertension

18

Timolol eye drops

Beta-blocker.
Reduction of intra-ocular pressure by reducing rate of production of aqueous humour.
Primary open-angle glaucoma.

19

Simvastatin.

Statin.
Inhibition of HMG-CoA reductase.
Hyperlipidaemia; prevention of MI in patients with atherosclerotic disease/diabetes mellitus

20

Dipyridamole

Antiplatelet drug.
Adjunct to anti-coagulation for thromboembolism prophylaxis

21

Gliclazide.

Sulfonylurea.
Enhances release of insulin from pancreatic beta cells.
Type 2 diabetes mellitus.

22

Zopiclone

Non benzodiazapene hypnotic.
Short term management of insomnia.

23

Quinine sulfate

Anti-malarial.
Falciparum malaria; nocturnal leg cramps.