E. Coli Flashcards Preview

RUSVM Bacteriology > E. Coli > Flashcards

Flashcards in E. Coli Deck (84)
Loading flashcards...
1

Characteristics of E. Coli

Lactose positive
Oxidative negative
Motile Rods

2

Pathogenicity

Facultative
Obligate pathogenic depending on age of host

3

O =

O Anitigen 26

4

H =

Flagella 11

5

F =

Fimbriae 41

6

K =

Capsule 60

7

ETEC

Enterotoxigenic

8

EHEC

Enterohemorrhagic

9

VTEC/STEC

Verotoxigenic/Shiga like toxic

10

EPEC

Enteropathogenic

11

RPEC

Rabbit pathogenic

12

APEC

Avian pathogenic

13

NTEC

Neurotoxigenic (cattle only)

14

F4

Only in pigs
Mannose resistant
Genes expressed at body temp

15

F5

Pigs and Bovine
Mannose resistant
Temp dependent
Only in young animals

16

F6

Neonatal animals

17

F18

Seen in edema

18

F41

Pigs and Bovine
Mannose resistant

19

Labile Toxin (LT)

Heat labile
Decrease Na+ absorption
Increase Cl- and HCO3+ secretion
Withstand 30 min at 60C

20

STa

Activation of guanylate cyclase system
Decrease Na+
Increase Cl- and HCO3+

21

STb

Increase prostaglandin E2

22

EAST1

Similar to STa

23

Stable Toxin

STa
STb
EAST1
Withstand 15 min at 121C

24

ETEC in Pigs - Symptoms

Smelly diarrhea
Dehydration

25

ETEC in Pigs - Target

Neonates - 2-4 wks

26

ETEC in Pigs - Virulence Factors - Neonate

F 4,5,6,41
STa,b EAST1, LT

27

ETEC in Pigs - Virulence Factors - Neo-Weaning

F4
LT, STa,b, EAST1

28

ETEC in Pigs - Epidemiology

Disruption of equilibrium between maternal immunity and infection pressure
Sow - MMA
Piglet - Low birthweight

29

ETEC in Pigs - Pathogenesis

Ascending from lower bowel --> oral uptake by host --> SI colonization
Requires - adhesion, multiplication, enterotoxins, secondary septicemia

30

ETEC in Pigs - Diagnosis

Agglutination test
PCR