efectos secundarios antineoplasicos y otros

Question 1

Polineuropatia distal + dysautonomic features, particularly constipation due to decreased gastrointestinal motility and, less frequently, orthostatic hypotension.

Answer 1

vincristine

Question 2

CYclofosfamida

causa? prevención?

Answer 2

cistitis hemorrágica

prevention: mesna

Question 3

Cisplatin / Carboplatin

Answer 3

dano a nervio acustico
nefrotoxico

Question 4

blomicina/ busulfan

Answer 4

fibrosis pulmonar

Question 5

ethambutol, efecto secundario?

Answer 5

color blindness

Question 6

dapsone, efecto secundario?

Answer 6

meteglobinemia

Question 7

rifampicina, efecto secundario?

Answer 7

orina anaranjado

Question 8

pulmonary fibrosis
hepatic toxicity
blue-grey skin discoloration

que medicamento?

Answer 8

amiodarona

Question 9

hiperplasia de encia

medicamento?

Answer 9

Ciclosporina

used for transplantation rejection prophylaxis

Side effects:

gingival hyperplasia,
and hirsutism,
hypertension,

Increased risk of carcinoma celulas escamosas de piel

Question 10

medicamentos q causan hiperplasia de encias

Answer 10

fenitoina
ciclofosfamida

Question 11

dolor a la palpacion del calcaneo + calf squeeze does not elicit pain

que medicamento tomo el pt?

Answer 11

Fluoroquinolonas —> rompimiento tendon de aquiles

Thompson test: test to diagnose Achilles tendon rupture. The patient lies prone with the feet hanging off the end of the bed, and the clinician squeezes the patient’s calf. Normally, passive plantar flexion is present. In complete Achilles tendon rupture, passive plantar flexion is absent.

Question 12

por que sucede warfarin-induced skin necrosis?

Answer 12

The anti-coagulants protein C and S are reduced early in warfarin therapy, leading to a(n) hypercoagulable state y skin necrosis

se evita dando enoxaparina por los primeros dias que se empieza warfarin