Elective Pregnancy Termination Flashcards

1
Q

What is the best method of pregnancy termination in a bitch not intended for breeding?

A

Ovariohysterectomy

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2
Q

Pregnancy Termination in Mares:
Before 35 days - __________________ injection of PGF2alpha is needed

A

Single

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3
Q

What is the method of pregnancy termination for the following species?
Mare

A

A single injection of PGF2alpha before 35 days of pregnancy

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4
Q

Why would we give oxytocin to a mare?

A

to cause big uterine contractions

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5
Q

Cattle are CL-dependent for the first part of their pregnancy and the last part of their pregnancy is when the _______________ takes over

A

Placenta

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6
Q

Prostaglandin drugs for cattle are:

A
  • Lutalyse
  • Cloprostenol
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7
Q

In cattle, after 150 days we have to do something to disrupt the placental source of progesterone. We do this by:

A

Giving Dexamethasone with the Prostaglandin (PGF2alpha)

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8
Q

(T/F) Goats are CL-dependent throughout their entire pregnancy

A

True

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9
Q

(T/F) In camelids, we can use either Lutalyse or Cloprostenol

A

False, we can only use Cloprostenol

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10
Q

Sheep are CL-dependent and then placental, just like the _______________

A

Cows

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11
Q

What is the method of pregnancy termination for the following species?
Goat

A

A single injection of dinoprost (LUTALYSE) at any point of pregnancy

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12
Q

What is the method of pregnancy termination for the following species?
Alpaca

A

A single injection of Cloprostenol (Estrumate) at any point of pregnancy

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13
Q

What is the method of pregnancy termination for the following species?
Bitch

A

Combination of PGF2alpha + dopamine agonist + prostaglandin E1

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14
Q

Dogs are a __________ dependent pregnancy

A

CL

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15
Q

A client with a valuable breeding bitch comes to you because she had an accidental breeding to her litter mate. She wants to know what the best option is in order to preserve her fertility. What is your recommendation?

A

Aglepristone (Alizin) injections

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16
Q

What is inversely proportional to Prolactin?

A

Dopamine (happy hormone)

17
Q

Aborted fetuses may be alive

A

Advanced pregnancy (>50 days)

18
Q
  • Shorter, but effective treatment
  • May pass aborted dead fetuses
A

Mid-pregnancy (30-40 days)

19
Q
  • Longer treatment times
  • Minimal vulvar discharge
A

Pregnancy diagnosis (25-30 days)

20
Q
  • Higher dose & longer duration of treatment
  • Few options
A

Early pregnancy (5-20 days diestrus)

21
Q

What are the reasons why the use of “mismate shot” (ECP) is not recommended?

A
  • Increased risk of cystic endometrial hyperplasia (CEH)
  • Increased risk of bone marrow suppression
  • Increased risk of pyometra
22
Q
  • Begin after day 35 gestation
    - If > day 50 gestation - live, nonviable pups delivered
  • Inexpensive
  • Preserves future fertility
  • 80% effective
A

Dexamethasone (Glucocorticoids)

23
Q
  • Stronger dopamine receptor (D2) agonist
  • Dose: 5 μg/kg PO SID x 5 days
    - Compounding often necessary
  • Minimal side effects (vulvar discharge)
  • No impact on fertility
  • Used with PGF2a
A

Cabergoline

24
Q
  • Veterinary compound approved in Europe
  • Progesterone Blocker
  • Two 10 mg/kg injections
    - SQ 24 hours apart
  • Fetal death within 5 days of treatment
    - Rare chance of treatment failure
    - Ultrasound needed to ensure efficacy
    - If still pregnant -> repeat injections
  • Can be used during “early” or “late” pregnancy
    - Early – 0-25 days
    - Late – 26-45 days
A

Aglepristone (Alizin®)

25
Q
  • Never used alone
  • Prostaglandin E1
  • Adjunctive therapy
  • Applied intravaginally or orally for cervical dilation
  • 100-400 µg per bitch q24h
  • Decreases treatment time
A

Misoprostol

26
Q
  • Reduce side effects
  • Treat earlier
  • Increase efficacy - Synergistic effect?
  • Shorten abortion times
A

Mismate Combos