Embryology Flashcards
(23 cards)
From what does the urogenital tract develop?
Intermediate mesoderm
From when does sexual differentiation occur?
7 weeks on
What triggers development of the male genital tract?
Sex determining region of Y (SRY) transcription factor
What do the somatic support cells differentiate into in males?
Sertoli cells
What does the male genital tract develop from?
Mesonephric (Wolffian) duct
What do sertoli cells produce?
Anti-Mullerian hormone
Stim production of Leydig cells
What do Leydig cells produce?
Testosterone
What does testosterone induce?
Formation of epididymis, vas deferens, seminal vesicles
What does Dihydrotestosterone (DHT) induce?
Male specific external genitalia
What does Persistent Mullerian Duct Syndrome produce?
Uterus, vagina and uterine tubes
Testes in ovarian location
Male external genitalia
What is an undescended testes called?
Cryptorchidism
When do male accessory glands develop?
10w
What are the three accessory glands in males?
Bulbourethral and prostate
Seminal vesicle
What stimulates the development of the female genital tract?
Absence of SRY transcription factor
What do somatic support cells differentiate into in females?
Granulosa cells
What do germ cells differentiate into in females?
Oocytes
What is a combination of an oocyte and granulosa cells called?
Primordial follicles
What ducts do the female genital tract develop from?
Paramesonephric (Mullerian) ducts
What do the Paramesonephric (Mullerian) ducts give rise to?
Uterine tubes
Uterus
Superior vagina
What are the three parts of the paramesonephric (Mullerian) ducts?
Cranial
Horizontal
Caudal
Name the 6 uterine abnormalities
Double uterus, double vagina Double uterus- 2x cervix + uterus Bicornate uterus- 2x uterus off 1 cervix Septate uterus Unicornuate uterus- 1 uterine tube Cervical atresia- No cervix
During what ages are the external genitalia indistinguishable?
Weeks 4-7
What is hypospadias?
External urethral opening not in glans
