Embryology of the Nervous System Flashcards Preview

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Flashcards in Embryology of the Nervous System Deck (90)
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1

notochord

iniates entire process of neurulation

signals formation of neural plate (thickened cells)
-dorsal surface of embryo

lateral edges start to fold

2

neural tube

formed from fusion of neural tube

3

cranial neuropore closure

day 25

4

caudal neuropore closure

day 27

5

neural tube

forms all of CNS
-brain and spinal cord

6

neural crest cells

form just above neural tube
-from neuroectoderm
-migrate into underlying mesoderm

become all of the PNS

7

fate of cranial neural crest

bones, cartilage, fascia, ligaments and tendons of face, neck

sensory ganglia and autonomic ganglia

8

fate of spinal neural crest

dorsal root ganglion
autonomic ganglion
heart - fibrous skeleton

9

shared fate of cranial and spinal neural crest

meninges
schwann cells
melanocytes

10

spinal cord formation

neural tube caudal to 4th pair of somites forms spinal cord

11

cells of neural tube

neuroectoderm
-migrate out away from lumen
-establish regions of spinal cord

12

zones of neuroectoderm migration

ventricular zone
mantle zone
marginal zone

13

ventricular zone

embryo - thick, pseudostratified epithelium called neuroepithelium

adult - simple layer of ependymal cells

14

derivatives of ventricular zone

give rise to all neurons and most glia of spinal cord

15

mantle zone

zone superficial to the neuroepithelium
composed of neuronal cell bodies
alar and basal plates

forms gray matter

16

sulcus limitans

separates basal and alar plates of mantle zone

17

basal plate

form motor, ventral horn

18

alar plate

form sensory, dorsal horn

19

marginal zone

outermost layer
composed of nerve processes (axons/dendrites)

form white matter

20

derivatives of neuroepithelium

neuroblasts
gliablasts

21

neuroblasts

form ventral horn motor neurons
and dorsal horn sensory neurons

22

gliablasts

form astrocytes and oligodendrocytes

23

spinal nerve

form from ventral root and dorsal root

24

dorsal root ganglion

derived from neural crest

25

microglial cells

derived from mesenchymal cells
migrate in later

26

cranial portion of neural tube

forms three vesicles

27

prosencephalon

forebrain

28

mesencephalon

midbrain

29

rhombencephalon

hindbrain

30

3 primary vesicles

prosencephalon
mesencephalon
rhombencephalon