Encephalitis Flashcards

1
Q

Cause of epidemic encephalitis

A

West Nile virus

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2
Q

Encephalomyelitis

A

Encephalitis with simultaneous involvement of spinal cord

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3
Q

General symptoms of encephalitis

A

HA, mild
Fever
Altered mentation
Focal neurologic deficit

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4
Q

Most common cause of sporadic encephalitis in the US

A

HSV-1

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5
Q

Positive sense, enveloped, ssRNA ARBOvirus of the flaviviridae family

A

West Nile virus

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6
Q

Vector of West Nile virus

A

Culex mosquito

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7
Q

Reservoir host for West Nile virus

A

Birds

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8
Q

Pt presents with flaccid paralysis, hyporeflexia, muscle weakness, tremors, ataxia, fever, and HA after spending time outdoors

A

West Nile virus encephalitis

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9
Q

DWI MRI reveals restricted diffusion in L or R medial temporal lobe

A

HSV I encephalitis

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10
Q

Treatment for HSV 1 encephalitis

A

Acyclovir

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11
Q

Envelopled, negative sense, ssRNA in a bullet-shaped capsule

A

Rabies

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12
Q

Primary source of rabies in US

A

Bats

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13
Q

Negri bodies

A

Eosinophilic cytoplasmic inclusions seen in rabies

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14
Q

Passive immunization after rabies exposure

A

Inject hyperimmune anti-rabies gamma globulin around wound site

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15
Q

Active immunization for rabies

A

5 doses of human diploid cell vaccine (HDCV)

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16
Q

High-risk populations for rabies

A

Spelunkers
Vets
*pets

17
Q

Non-enveloped DNA polyoma virus

A

JCV

18
Q

Reactivation due to immunosuppression of this virus leads to demyelination of oligodendrocytes in this condition

A

JCV progressive multifocal leukoencephalopathy

19
Q

Insidious onset of focal neurological deficit in immunocompromised

A

JCV PML encephalitis

20
Q

Rare progressive clinical syndrome characterized by cognitive decline, limb spasticity, and seizures

A

Subacute sclerosing panencephalitis (SSPE)

21
Q

Encephalitis characterized by widespread gliosis and myelin degeneration with viral inclusions and neurofibrillary tangles

A

SSPE

22
Q
A