Meningitis

Question 1

Classic triad of symptoms in meningitis

Answer 1

Fever
HA
Neck stiffness

Question 2

Pathogens associated with community acquired meningitis

Answer 2

Strep pneumoniae
Neisseria meningitidis
Listeria monocytogenes
Haemophilus influenzae

Question 3

Pathogens associated with hospital acquired meningitis

Answer 3

S aureus
S epidermidis
Pseudomonas
E. coli
Enterococcus faecalis
Haemophilus influenzae

Question 4

Common causes of bacterial meningitis in neonates

Answer 4

E coli
GBS - strep agalactiae
Listeria monocytogenes
Enteroviruses

Question 5

CSF shows lymphocytes, normal glucose, and moderately high protein. It is clear.

Answer 5

Viral meningitis

Question 6

Bacteria that can cause chronic meningitis

Answer 6

Mycobacterium tuberculosis

Question 7

Fungus that can cause chronic meningitis

Answer 7

Cryptococcus neoformans

Question 8

Causal organisms of eosinophilic meningitis

Answer 8

Parasite larva

Angiostrongylus contonensis
Baylisascaris procyonis

Question 9

Causal organisms of nosocomial meningitis

Answer 9

S aureus
S epidermidis
Enterococcus fecalis

Question 10

Gram negative diplococci with capsule and pili that produces LOS endotoxin

Answer 10

Neisseria meningitidis

Question 11

Likely pathogen in meningitis with petechia/purpura

Answer 11

Neisseria meningitidis

Question 12

Complications of Neisseria meningitidis

Answer 12

DIC/septic shock
Adrenal necrosis
Endotoxic shock

Question 13

Waterhouse Friedrichsen syndrome

Answer 13

Adrenal necrosis

Question 14

Treatment for Neisseria meningitidis

Answer 14

Ceftriaxone
Cefotaxime
Penicillin
Meropenem
Chloramphenicol –> if allergy to beta-lactam

Question 15

Chemoprophylaxis for Neisseria meningitidis

Answer 15

Rifampin and cipro

Question 16

Gram negative polymorphic bacteria with cocci, bacilli, and coccobacilli

Answer 16

Haemophilus influenzae B

Question 17

Bacteria with Hib capsule and PRP that produces LOS endotoxin

Answer 17

Haemophilus influenzae B

Question 18

Haemophilus influenzae B is seen most often in what age groups

Answer 18

Infants
Elderly

Question 19

Gram positive capsule with teichoic and lipoteichoic acids, and pneumolysin

Answer 19

Streptococcus pneumoniae

Question 20

Alpha hemolysis and optochin sensitive on blood agar with latex agglutination

Answer 20

Streptococcus pneumoniae

Question 21

Meningitis pathogen associated with recurrent otitis media

Answer 21

Strep pneumoniae

Question 22

Treatment for strep pneumoniae meningitis

Answer 22

Third gen cephalosporins
Penicillin
Fluoroquinolones
Vancomycin

Question 23

Gram positive, short bacilli with actin tails

Answer 23

Listeria monocytogenes

Question 24

Exotoxin produced by Listeria monocytogenes

Answer 24

Listeriolysin O

Question 25

Beta hemolysis on blood agar and tumbling motility

Answer 25

Listeria monocytogenes

Question 26

Treatment of Listeria monocytogenes

Answer 26

Synergic cell wall acting abx with an aminoglycoside

Question 27

Gram negative rod with K capsule virulence and pink colonies on lactose colonies

Answer 27

E coli

Question 28

Gram positive cocci in chains with beta hemolysis on blood agar and is catalase negative

Answer 28

GBS

Question 29

Treatment for GBS meningitis in neonates

Answer 29

Ampicillin plus aminoglycoside Erythromycin

Question 30

Complication of in utero transmission of listeria monocytogenes

Answer 30

Amnionitis and fetal death

Question 31

Ascending/ruptured membranes, granulomatosis infantisepticum, sepsis, and meningitis is associated with what

Answer 31

Early onset listeria monocytogenes in neonates

Question 32

Gram positive coccobacilli, tumbling motility, cold growth, catalase positive, and weakly beta hemolytic on blood agar

Answer 32

Listeria monocytegenes

Question 33

Enteroviruses associated with neonatal meningitis

Answer 33

HSV II VZV CMV

Question 34

Non-enveloped, positive sense, ssRNA enteroviruses associated with meningitis

Answer 34

Coxsackie ECHO Polio/Picornaviridae

Question 35

Rodent borne virus that can cause meningitis

Answer 35

Lymphocytic choriomeningitis

Question 36

Pathogen that can cause meningitis that stain pink with mucicarmine, has latex agglutination, and its capsule is visualized on India ink

Answer 36

Cryptococcus neoformans

Question 37

Pathogen that can cause meningitis that is spread via inhalation of contaminated pigeon droppings

Answer 37

Cryptococcus neoformans