Endocrine

Question 0

Corticroph adenoma devt after surgical removal of adrenal glands

Answer 0

Nelson syndrome

Question 1

Pituitary apoplexy triad

Answer 1

HA
Diplopia
Hypopituarism

Question 2

Water deprivation test
CDI
NDI

Answer 2

UOsm inc >50% from baseline

<50% from baseline

Question 3

MCC of SIADH

Answer 3

Small cell lung ca

Chlorpropramide

Question 4

MCC pediatric hypopituitarism
Rathke’s pouch remnants
WNT

Answer 4

Craniopharyngoma

Question 5

2 types of craniopharyngoma

Answer 5

Adamantinomatous children wet keratin lamellar

Papillary adult

Question 6

Hypothyroidism
Children
Adult

Answer 6

Cretinism

Myxedema (Gull disease)

Question 7

Somatotroph adenoma
Children
Adult

Answer 7

Gigantism

Acromegaly

Question 8

CTL4 polymorphisms
MCC hypothyroidis
Anti thyroglobulin
Anti TPO
Atrophic thyroid follicles lined by Hurthle cells

Answer 8

Hasimoto thyroiditis

Question 9

Coxsackievirus
MCC painful thyroid gland
Multinucleate giant cells

Answer 9

Subacute De quervain thyroiditis

Question 10

Painless thyroiditis

Postpartum

Answer 10

Lymphocytic thyroiditis

Question 11

Woody or fibrous thyroid

Answer 11

Reidel thyroiditis

Question 12

Diffuse thyroid hypertrophy and hyperplasia

Infiltrative ophthalmopathy

Answer 12

Graves disease

Question 13

Multi lobulated goiter grows behind sternum and clavicles

No capsule between hyperplastic nodules and residual compressed thyroid

Answer 13

Intrathoracic or plunging goiter
Vs follicular ca

MNTG

Question 14

Autonomous nodule in long standing goiter producing hyperthyroidism

Answer 14

Plummer syndrome

Question 15

Follicular adenoma with oxyphilia

Answer 15

Hurthle cell adenoma

Question 16

MC primary thyroid ca in adults
Orphan Annie
Psamomma bodies
Lymphatic

Answer 16

Papillary thyroid cancer

Question 17

Solitary cold nodule
Dietary iodine deficiency
Bone mets

Answer 17

Follicular thyroid ca

Question 18

Past history of well differentiated tumor
Worst prognosis
Pleomorphic giant cells mixed with sarcomatous spindle cells
Cytokeratin marker

Answer 18

Anaplastic thyroid ca

Question 19

Parafollicular cell origin
Calcitonin
Neuroendocrine
Acellular amyloid deposits
C cell hyperplasia

Answer 19

Medullary thyroid ca

Question 20

MCC primary hyperPTH
Centrally placed nuclei
Endocrine atypia

Answer 20

Parathyroid adenoma

Question 21

Water clear cell hyperplasia

Answer 21

Primary hyperplasia

Question 22

MCC secondary hyperPTH

Answer 22

Renal failure

Question 23

MCC hypoPTH

Answer 23

Previous thyroid surgery

Question 24

Autoantibodies of T1DM

Answer 24

Anti insulin Anti GAD Anti ICA512

Question 25

MCC death in diabetics

Answer 25

MI

Question 26

Capillary BM thickening Diffuse mesangial sclerosis Nodular glomerulosclerosis

Answer 26

Kimmelstein wilson nodules | DM

Question 27

Renal papillary necrosis

Answer 27

Pyelonephritis

Question 28

MC pancreatic endocrine neoplasm

Answer 28

Insulinoma

Question 29

Whipple triad

Answer 29

Hypoglycemia sx Low plasma glucose Relief of sx upon glucose administration Insulinoma

Question 30

Solitary tumors composed of giant islet cells and amyloid deposits Islet hyperplasia

Answer 30

Nesidioblastosis | Insulinoma

Question 31

Mild DM Necrolytic migratory erythema Anemia

Answer 31

A cell tumors | Glucagonomas

Question 32

MCC hypercortisolism (Cushing syndrome)

Answer 32

Exogenous glucocorticoids

Question 33

Pale and homogenous pituitary gland

Answer 33

Crooke Hyaline change | Hypercortisolism

Question 34

High dose dexamethasone Cortisol levels ACTH levels

Answer 34

Pituitary CS low high Adrenal CS normal low Ectopic CS normal high

Question 35

MC sign of primary hyperaldosteronism

Answer 35

Hypertension

Question 36

Renin levels Primary Hyperaldosteronism Secondary

Answer 36

Dec | Inc

Question 37

Eosinophilic laminated cytoplasmic inclusions

Answer 37

Spironolactone bodies | Aldosterone producing adenomas

Question 38

MC enzyme deficiency in CAH

Answer 38

21 hydroxylase deficiency

Question 39

``` Lipid depleted cells Corticorroph hyperplasia in pituitary Inc 17 ketosteroids 17 hydroxyprogesterone Dec 27 hydroxycorticoids ```

Answer 39

CAH

Question 40

Pheochromocytoma | 10

Answer 40

``` Extraadrenal (parangangliomas) B Malignant Not hpn Germline mutation ```

Question 41

Zellballen Salt and pepper chromatin Chromogranin and synaptophysin neuroendocrine markers

Answer 41

Pheochromocytoma

Question 42

Parathyroid adenoma or hyperplasia Pancreatic tumors Pituitary tumors esp prolactinoma

Answer 42

Men 1 wermer syndrome

Question 43

Pheochromocytona Medullary ca Parathyroid hyperplasia

Answer 43

Men 2a sipple syndrome

Question 44

Pheochromocytoma Medullary ca Neuromas or ganglioneuromas

Answer 44

Men 2B