Endocrine

Question 1

excessive generalized bone and tissue growth before 18 years

Answer 1

gigantism

Question 2

overgrowth of tissue and bone after the age of 18 years

Answer 2

acromegaly

Question 3

protruding/lantern jaw, large spade-like hands, visual disturbance

Answer 3

acromegaly

Question 4

excess ACTH due to functioning pituitary adenoma

Answer 4

Cushing disease

Question 5

moon-face, buffalo hump, obesity and purple striae on the abdomen

Answer 5

Cushing disease

Question 6

growth hormone deficiency in children

Answer 6

pituitary dwarfism

Question 7

ischemic necrosis of pituitary gland after pospartum hemorrhange

Answer 7

Sheehan’s syndrome

Question 8

Amenorrhea, no lactation and loss of axillary hair after delivery

Answer 8

Sheehan’s syndrome

Question 9

amenorrhea, galactorrhea, and infertility

Answer 9

prolactinoma

Question 10

polyuria, polydypsia but no polyphagia after head injury

Answer 10

diabetes insipidus

Question 11

low thyroid levels in infancy with mental retardation

Answer 11

cretinism

Question 12

low thyroid levels in adult, slow to relax reflexes and old interolerance

Answer 12

hypothyroidism

Question 13

commonest cause of hypothyroidism in US

Answer 13

Hashimoto’s disease

Question 14

polyuria, constant urinary specific gravity in spite of dehydration

Answer 14

diabetes insipidus

Question 15

high TSH, low T3 and T4

Answer 15

primary hypothyroidism

Question 16

low TSH, low T3 and T4

Answer 16

secondary hypothyroidism

Question 17

anti-thyroglobulin antibodies, goiter and hypothyroidism

Answer 17

Hashimoto’s disease

Question 18

bulging eyes, heat intolerance, increase appetite but weight loss

Answer 18

hyperthyroidism

Question 19

hyperthyroidism with TSH antibodies

Answer 19

Grave’s disease

Question 20

hyperthryoidism with multiple nodular goiter

Answer 20

Plummer’s disease

Question 21

high TSH with elevated T3 and T4

Answer 21

secondary hyperthyroidism

Question 22

Low TSH with raised T3 and T4

Answer 22

primary hyperthyroidism

Question 23

fatigue, brown bone cysts and hypercalcemia

Answer 23

hyperparathyroidism

Question 24

tetany, muscle spasm and a positive Chvosteck sign

Answer 24

hypoparathyroidism

Question 25

tapping the facial nerve in front of the ear causes the face to twitch

Answer 25

Chvosteck test

Question 26

hyperpigmented skin creases, low BP, low NA and high K

Answer 26

Addison's disease

Question 27

Low K, low rennin, high BP and metabolic alkalosis

Answer 27

Conn's disease

Question 28

moon face, truncal obesity, purple abdominal striae

Answer 28

Cushing's syndrome

Question 29

most common adrenal tumor in children

Answer 29

neuroblastoma

Question 30

10% tumor, palpitations, sweating, headaches, hypertension

Answer 30

pheochromocytoma

Question 31

10% are bilateral, malignant, familial and occurs outside the adrenals

Answer 31

10% tumor

Question 32

polyuria, polydypsia, polyphasia, pruritis

Answer 32

diabetes mellitus

Question 33

insulin def due to beta cell destruction

Answer 33

DM type 1

Question 34

insulin insensitivity associated with obesity

Answer 34

DM type 2

Question 35

Kussmaul's respiration and ketonuria are seen more in DM type 1

Answer 35

diabetic ketoacidosis

Question 36

more seen in DM type 2

Answer 36

hyperosmolar non-ketosis

Question 37

bouts of recurrent diarrhea, cutaneous flushing and wheezing

Answer 37

carcinoid syndrome

Question 38

bouts of hypoglycemia relieved by eating food

Answer 38

insulinoma

Question 39

recurrent peptic ulcer disease

Answer 39

Zollinger-Ellison syndrome