Endocrine Flashcards Preview

Pediatrics > Endocrine > Flashcards

Flashcards in Endocrine Deck (18)
Loading flashcards...
1
Q

What is the predominant fetal thyroid?

A

Reverse T3 which is inactive

2
Q

What happens to TSH after birth?

A

Surge causing high t3,4

3
Q

Preterm infants have which T is low?

A

T4

4
Q

Why screen congenital hypothyroidism ?

A

A preventable cause of severe learning difficulties

5
Q

The most common cause of sporadic congenital hypothyroid ?

A

Maldescent or athyrosis

6
Q

The most common cause of congenital hypothyroidism worldwide?

A

Iodine deficiency’s

Prevented by iodination of salt

7
Q

When to suspect TSH deficiency as the cause of hypothyroid ?

A

When there is decrease GH, GRH, ACTH deficiency manifestied in
Hypoglycemia
Micropenis
Undescended testis

8
Q

Treatment with thyroxine should start when??

A

Before 2/3 weeks of age to reduce impairment of neural development

9
Q

Who has the risk of autoimmune hypothyroiditis and other autoimmune disorder?

A

Down and turners

10
Q

Biochemical findings in hyperthyroidism ?

A

Thyroid stimulating immunoglobulin causing the disease

Anti thyroid Peroxisomal antibodies may also be present then causing hypothyroid by trying to resolute the hyper

11
Q

Treatment of hyperthyroid?

A

Carbimazole or propylthiouracil

12
Q

Side effect of anti thyroid and when to screen?

A

Neutropenia

If develops sore throat and high fever

13
Q

Symptomatic relief of anxiety tremor and tachycardia by?

A

Beta blockers

14
Q

If relapse after 2 years of medication, treatment option include?

A

Second corse of medications or radioiodine treatment

Subtotal thyroidectomy surgery

15
Q

Functions of parathyroid hormone

A

1 bone formation via osteoblasts
2 when Ca is low bone resorption via osteoclasts
3 increases renal uptake of Ca
Activated metabolism of vitamin D to promote gut absorption of Ca

16
Q

If PTH LOW ?

A

Ca low
Phosphate high
NORMAL ALP

17
Q

Hypocalcemia causes?

A
Fits
Spasms
Stridor
Diarrhea 
\+ rickets
18
Q

Causes of hypoparathyroidim in
Infants
Older children?

A

Digeorge

Autoimmune Associated with Addison