Endocrine and Aging

Question 1

Four hormones that decrease during aging

Answer 1

Estrogen, Testosterone, DHEA (androgen), GH/IGF-1

Question 2

What hormone stays the same during aging

Answer 2

cortisol

Question 3

Three major risks of estrogen + progesterone therapy in the women’s health initiative

Answer 3

Heart disease, Breast Cancer, Stroke

Question 4

Women’s Health Initiative effect of estrogen only

Answer 4

no significant difference in any benefit of estrogen

Question 5

What is the consensous of giving ERT during menopausal symptoms

Answer 5

give it at the lowest dose only when women are symptomatic then taper it off

Question 6

Young men are lowest T during this time of day, while older men are low when?

Answer 6

Young men low T during late afternoon

Old men low T consistently

Question 7

Test T when?

Answer 7

Early morning

Question 8

Don’t check T levels when the patient is

Answer 8

sick

Question 9

How does GH pulsatility change with age?

Answer 9

Same frequency but lower amplitude

Question 10

What hormone increases as you age and what are the effects?

Answer 10

Cortisol, increases insulin resistance

Question 11

What hormonal change has a different presentation in the elderly? What symptom is more present in hyper/hypo?

Answer 11

Hyper/hypothyroidism; hyper- apathy, anorexia; hypo- weight loss, anorexia

Question 12

TSH and T4 levels for subclinical hypothyroidism

Answer 12

High TSH, normal T4

Question 13

Increased T4 may cause an increase in what?

Answer 13

Atrial Fibrillation

Question 14

___ and subclinical hypothyroidism are linked strongly

Answer 14

Diabetes