Parathyroid and Calcium

Question 1

PTH causes bone

Answer 1

resorption

Question 2

PTH effect on Ca andVit D n the kidney

Answer 2

Reabsorbs Ca and adds second hydroxy group to D

Question 3

Net total effect of PTH

Answer 3

increases serum Ca levels

Question 4

Most common cause of Parathyroid hypersecretion of PTH

Answer 4

solitary adenoma

Question 5

Vit D effect on Gut Ca

Answer 5

increases gut’s absorption of calcium and phosphate

Question 6

Net effect of PTH on phosphate

Answer 6

Loss of phosphate because you piss it all out

Question 7

Primary hyperparathyroidism clinical findings

Answer 7

Bones, Groans (pancreatitis), Stones (kidney, stomach ulcers) , Psychic moans

Question 8

Previous severe bone disease found with high PTH levels

Answer 8

osteitis fibrosa cystica

Question 9

Today high PTH people only present with

Answer 9

elevated serum Ca

Question 10

Primary hyperparathyroidism mostly affects ___ bone

Answer 10

cortical

Question 11

Symptomatic patients with these two symptoms are candidates for Primary hyperparathyroidism surgery

Answer 11

fractures, kidney stones

Question 12

Asymptomatic patients younger than __, with severe ___, with reduced ____ clearance, and low __ __

Answer 12

50, hypercalcemia, creatinine clearance, bone mass

Question 13

Secondary hyperparathyroidism is caused by the parathyroid glands compensating for

Answer 13

hypocalcemia

Question 14

Secondary hyperparathyroidism causes

Answer 14

renal insufficiency, calcium malabsorption, Vit D deficecny

Question 15

Tertiary hyperparathyroidism comes after prolonged __ and one of the glands goes rouge

Answer 15

Secondary hyperparathyroidism

Question 16

Secondary vs. Tertiary- Calcium and PTH levels

Answer 16

Secondary - Low Ca, High PTH

Tertiary- High Ca, High PTH

Question 17

Familial Hypocalciuric Hypercalcemia is an inactivation mutation of what receptor?

Answer 17

The calcium sensing receptor

Question 18

Lab findings for FHH

Answer 18

High Serum Ca, Normal/Slight high PTH, LOW URINE CALCIUM

Question 19

FHH outcomes

Answer 19

Benign, no surgery history

Question 20

Activating the calcium sensing receptors is done by high __ levels and results in what

Answer 20

calcium, bone formation, decreased bone resorption

Question 21

Most common cause of Hypoparathyroidism

Answer 21

post surgical

Question 22

Most concerning symptom of Hypoparathyroidism

Answer 22

cardiac arrhythmia

Question 23

Other symptoms of Hypoparathyroidism

Answer 23

Tingling of fingers/toes, tetany of facial nerve or carpal spasm

Question 24

What is the goal of serum calcium level in a Hypoparathyroidism patient

Answer 24

low normal so you don’t give em kidney stones

Question 25

Vitamin D toxicity takes ___ amount and has these symptoms

Answer 25

a fuck ton; nausea, altered mental status

Question 26

Vitamin D deficiency etiology

Answer 26

liver issues, kidney issues, too little intake, too little sun

Question 27

Vitamin D deficiency results in

Answer 27

secondary hyperparathyroidism

Question 28

Vitamin D deficiency causes __ bone disease in kids- common symptom

Answer 28

rickets, bowing of the legs

Question 29

Vitamin D is responsible for bone

Answer 29

mineralization