Endocrine System Flashcards

(50 cards)

1
Q

Endocrine System

A

collection of cells, tissues and glands that play an important role with the CNS in the maintenance of homeostasis

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2
Q

maintenance of an internal environment at a set point in the face of changing external environment

A

homeostasis

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3
Q

It is a central mechanism through which cells communicate with other cells and regulate physiological processes

A

Endocrine

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4
Q

The endocrine system differs from the CNS in that ___ cells release chemical messengers known as ___

A

endocrine

hormones

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5
Q

travel to target cells through the blood

A

hormones

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6
Q

release chemical messengers (hormones) into the blood stream.

A

endocrine cells

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7
Q

only cells with receptors for that a particular hormone will respond

A

endocrine cells

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8
Q

In concert with the CNS, the endocrine system regulates a wide range of physiological processes including, but not limited to, ____, _____, ____, and _____ ____.

A

metabolism
growth
development
sexual reproduction

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9
Q

the endocrine system is very __ and ____.

A

diverse

decentralized.

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10
Q

releasing and inhibitory hormones

A

hypothalamus

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11
Q

systemic hormones

A

pituitary gland

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12
Q

Leptin

A

adipose

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13
Q

Atrial natriuretic factor

A

Heart

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14
Q

Erythropoietin
and
Insulin like growth factor (IGF)

A

Liver

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15
Q

Steroids

catecholamine

A

Adrenal glands

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16
Q

estrogen

inhibin

A

ovaries

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17
Q

Melatonin

A

Pineal Gland

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18
Q

Thyroxine

A

Thyroid

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19
Q

parathyroid

calcitonin

A

Parathyroid

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20
Q

Gastrin

A

Stomach

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21
Q

Insulin

Glucagon

22
Q

Calcitriol

Angiotensin II

23
Q

Secretin

24
Q

Testosterone

Inhibin

25
Modified epithelium and neurons have ___ ___
endocrine functions
26
Most endocrine cells are commonly derived from ___ ___and are found inside an ___ or a distinct ___ ___.
secretory epithelium organ endocrine gland
27
Secretes hormone into blood can be a neuron is found as part of the organs like the heart s found within endocrine glands
endocrine cells
28
Regulation of a wide range of physiological processes Variety in chemical structure Released in very low quantities (10-11 M) Movement solely through diffusion (and through the plasma) Binding to receptors on target cells Release in response to changes in homeostasis
General Properties of hormones
29
cell may release a chemical message onto itself
autocrine effect
30
a cell may release a chemical messenger into the interstitial fluid onto neighbors
paracrine effect
31
_____ can be a neurotransmitter when released to neurons, but a hormone when released into the blood
Norepinephrine
32
Cellular metabolism Tissue maturation Blood levels of several critical ions The body’s fluid balance The production of immune cells The cardiovascular system Blood levels of a wide range of nutrients Reproduction, and parturition (birthing)
Processes regulated by the endocrine system
33
If target cells remove receptors from the plasma membrane decreasing receptor levels on target cells
downregulation
34
increasing the expression of receptors for a hormone increasing receptor levels on target cells
up regulation
35
process of hormones regulating the expression of receptors for other hormone
permissiveness
36
Are found throughout the body Express a receptor for that hormone Convert the information carried in the hormone structure into a cellular signal Play key roles in the regulation of physiological processes
Hormone target cells
37
___ don't approach zero | instead they fluctuate between high and low (amplitude)
hormones
38
release is an all-or-none process that varies in its frequency (frequency)
neurotransmitter
39
Peptide and protein Hormones are synthesized in an Inactive form
encoded by genes
40
Synthesis of Amini Acid Derivative Hormones
biochemically synthesized from amino acids stored with vesicles
41
changes in a critical physiological factor to input from the nervous system directly through the release of neurohormones the actions of other hormones In response to mechanical stresses (heart atria) or cellular metabolism
Hormone secretion is regulated by:
42
The lipid-soluble hormone is transported ___________.
complexed to carrier proteins
43
smaller than kidney filtration barrier | excreted in urine
water soluble free hormone
44
Some excreted in urine | otherwise excreted in GI tract
lipid soluble hormone
45
time required to reduce blood concentration of hormones by 50%
half time
46
metabolism can change ___ levels or activity
hormone
47
integral membrane proteins extracellular region binds hormone intracellular region interacts with G protein
G-protein coupled receptor (GPCRs)
48
is a compound that can bind to a hormone receptor and produce the same effects as the hormone
. An agonist
49
Integral membrane proteins Extracellular region binds hormone Intracellular region contains a kinase domain; directly activates enzymes without G-proteins
One Transmembrane Spanning Receptors (1-TMS)
50
Found inside the cell Act as transcription factors Generally cytoplasmic proteins complexed with heat shock proteins (HSPs) Hormone binding leads to dissociation of HSPs, dimerization to a second bound receptor, and translocation to the nucleus
Nuclear Receptors