Endocrinology of Aging Flashcards Preview

Endo/Repro Exam 2 > Endocrinology of Aging > Flashcards

Flashcards in Endocrinology of Aging Deck (16):
1

What are two hormone systems that do not use the HPA axis?

Insulin/glucagon
Parathyroid/calcitonin

2

What are the two important clinical changes in endocrine activity of old people?

Pancreas
Thyroid

3

Four components of treatment:

1.) Diet
2.) Exercise
3.) Hypoglycemic agents
4.) Insulin

4

What are the endocrine and exocrine functional components of the pancreas?

Acinar: exocrine
Islet of Langerhans :endocrine

5

What are the two possible thyroid changes in older patients?

Hyper or hypothyroidism (can be either)

6

What are the adverse effects of hyperthyroidism in older?

Increased ischemic heart disease
Atrial fibrillation

7

Hypothyroidism adverse effects in older patients?

Not really any

8

When is hyperthyroidism treated in older individuals?

TSH less than 0.1 mU/L in 65 or older and in patients with cardiac risk, heart disease, osteoporosis

9

What is done in hyperthyroid patients with TSH between 0.1 and 0.5 mU/L?

Only if 65 or older and cardiac disease or hyperthyroid symptoms

10

What is the typical thyroid serum profile of older patients?

Lower T4 levels
Elevated TSH levels

11

What is perimenopause?

Time during the onset of menopause

12

When do you treat women for perimenopause?

Only if they are suffering from the menopause symptoms

13

What causes menopause symptoms?

An increase in P4 production (hot flashes)

14

What is the difference in estrogen and testosterone levels in aging patients?

Estrogen is high until menopause and spikes
Testosterone slowly decreases steadily throughout life

15

What occurs to GH and IGF-1 as you age?

It decreases

16

What is the shift in cortisol release as you get older?

Young: highest at early morning and sleeping; low in evening
Old: High in late morning and high in the evening