Male and Female Pubertal Development Flashcards Preview

Endo/Repro Exam 2 > Male and Female Pubertal Development > Flashcards

Flashcards in Male and Female Pubertal Development Deck (34):
1

What is thelarche?

Onset of breast development, an estrogen effect

2

What is pubarche?

Onset of sexual hair growth, an androgen effect

3

What is menarche?

Onset of menses

4

What is spermarche?

Appearance of sperm in seminal fluid

5

What is gonadarche?

Onset of pubertal function of the gonads

6

What is adrenarche?

Onset of adrenal androgen production

7

What is a better marker for determining when a child will enter puberty: bone age or chronological age?

Bone age

8

What is the role of fat and beginning of puberty?

A critical amount of body fat is the weight-related trigger for pubertal development

9

What is released by fat cells to cause GnRH release?

Leptin

10

What is precocious puberty?

Premature puberty

11

What is considered precocious puberty in females?

Thelarche or pubarche before 8 years of age

12

What is considered precocious puberty in males?

Pubarche or genital development before 9 years of age

13

What race is thelarche normal in girls at age 7?

African American
Mexican American

14

Effect of precocious puberty on height?

Premature closure of epiphyseal plates and short stature despite tall stature in childhood

15

What is premature thelarche usually due to?

Minimal activation of the hypothalamic-pituitary-ovarian axis with predominant FSH secretion

16

How is delayed puberty defined in females?

Lack of breast development by age 13

17

How is delayed puberty defined in males?

Lack of pubertal testicular development by age 14

18

What is the state of the HPG axis in childhood?

Dormant

19

What is the HPG axis state in females beginning puberty?

Ovarian secretion of estradiol peaks during the day

20

What is the HPG axis state in males beginning puberty?

Testicular production of testosterone peaks during sleep

21

Estradiol effects on linear growth?

Low level: enhances linear growth
High level: increases rate of epiphyseal fusion

22

What does progesterone cause in breast?

Lobuloalveolar breast development

23

What neurotransmitters are stimulants in puberty?

Kisspeptin
Glutamate
Leptin

24

What neurotransmitters are inhibitors of puberty?

GABA
Neuropeptide Y
TGF-Beta

25

Progression of pubertal development in females?

Thelarche -> Growth Spurt -> Pubarche -> Menarche

26

Progression of pubertal development in males?

Testicular enlargement -> Penile and scrotal growth -> Pubarche -> Growth Spurt

27

What Tanner stage does linear growth occur in males?

3 and 4

28

What does Tanner staging describe?

Breast development in males
External genitalia development in males
Pubic hair development in both

29

Difference in breast Tanner stage III and IV?

III: Enlargement of breast and areola with no separation of areolar contour from breast
IV: Areola and papilla project above breast forming a secondary mound

30

Difference in male genitalia Tanner stage IV and V?

IV: Pubic hair is only on mons pubis
V: Pubic hair on thighs and up abdomen

31

What hormones are primarily responsible for linear growth?

GH and Testosterone

32

What hormones is primarily responsible for stopping linear growth?

Estrogen

33

What Tanner stage does linear growth start in females?

Stage 2

34

What is constitutional delay of puberty?

Late bloomers that has a family history of late bloomers