Endrocrinolgy of Excercise and Stress Flashcards Preview

Endo/Repro Exam 2 > Endrocrinolgy of Excercise and Stress > Flashcards

Flashcards in Endrocrinolgy of Excercise and Stress Deck (18):
1

What are the effects of norepinephrine and epinephrine on insulin?

Inhibits the release of insulin so that GLUT-4 cannot uptake glucose and GLUT-1 in muscle cells can take glucose still

2

Effects of muscle contraction and glycogenolysis?

Contraction leads to increased Ca ions; Ca ions bind to calmodulin which then directly activates phosphorylase kinase increasing glycogen degradation

3

What occurs to the RAAS axis during exercise?

Increase in aldosterone renin and ANP at 25-40% VO2 max
A-II and ADH increase at 60-80% VO2 max

4

What occurs to the HPA axis with exercise?

During stress of exercise: IL-6 increases-> increase in CRH and AVP -> ACTH

5

What does the increase of CRH, cortisol and beta-endorphin cause in exercise?

CRH inhibits GnRH and therefore LH and FSH

6

What does IL-6 cause?

Stimulation of CRH and ADH secretion leading to cortisol release

7

What is the female athlete triad that leads to exercise induced amenorrhea?

Eating disorder
Hypothalamic amenorrhea
Osteoporosis

8

What does extensive exercise cause in males?

Suppression of LH and testosterone levels

9

What is the term for healthy homeostasis?

Eustasis

10

What is term for different homeostasis?

Allostasis

11

What is the term for defective homeostasis?

Cacostasis

12

What part of the brain does the stress system activate?

Amygdala: Fear
Hippocampus: Anger and memory

13

What is the locus ceruleus?

Adrenal gland of the CNS

14

Where is the locus ceruleus located?

Dorsal wall of the pons

15

What does the locus ceruleus produce?

NE in the brain

16

What occurs in fight or flight?

Locus ceruleus releases NE in the brain and it only circulates in the brain

17

Cortisol effects on the immune system?

Promotes of neutrophil movement from bone marrow to circulation
Reduces lymphocytes in circulation to spleen, thymus, bone marrow

18

When is ACTH and Cortisol highest in normal people?

High in morning
Low at night
Spikes randomly in the day