Endometrium Flashcards Preview

Ch. 13 Female Genital and Gestation > Endometrium > Flashcards

Flashcards in Endometrium Deck (19):
1

Asherman syndrome

aggressive D&C
scrapes away basal layer of endometrium
secondary amenorrhea

2

Anovulatory phase
hormonal causes

unopposed estrogen
no progesterone to start ovulation phase

3

Acute endometritis
etiology

retained products of conception

4

Chronic endometritis
etiologies
defining pathological feature

PID, IUD, TB
plasma cells are defining feature
*lymphocytes are always present in endometrium

5

Endometrial polyps are commonly due to

tamoxifen exposure
weak agonist in uterus
growth of polyps

6

Endometriosis is what

endometrial tissue (glands and stroma) found in non-endometrial locations

7

What is endometriosis of the myometrium called?

adenomyosis

8

Most common site of endometriosis

ovary
formation of chocolate cyst

9

Endometriosis of soft tissue
lesions

gun powder lesions

10

Endometriosis of fallopian tubes may cause

infertility 2˚ to endometrial scarring

11

Endometrial hyperplasia
etiology

hyperplasia of endometrial glands relative to stroma
2˚ to unopposed estrogen exposure

12

Endometrial hyperplasia
pre- or post-menopausal

post-menopausal

13

Classification of endometrial hyperplasia

simple or complex
± cellular atypia

14

Endometrial carcinoma
pathways

from endometrial carcinoma
-dependent on unopposed estrogen
sporadic
-due to de novo p53 mutations

15

Sporadic endometrial carcinoma
histology findings

psammoma body formation

16

Histology of endometrial carcinoma
from hyperplasia pathway

"endometriod" appearance
looks similar to normal endometrium

17

Leiomyomas
etiology
progression/regression phases

estrogen exposure
progresses during pregnancy
regresses after menopause
*no risk of progression to leiomyosarcoma

18

Etiology of leiomyosarcomas

NOT FROM LEIOMYOMAS
arise do novo in post menopausal women

19

Gross differences between leiomyoma and leiomyosarcoma

leiomyoma: multiple, white whorled masses
leiomyosarcoma: usually solidtary, necrosis and hemorrhage