Vulva Flashcards Preview

Ch. 13 Female Genital and Gestation > Vulva > Flashcards

Flashcards in Vulva Deck (14):
1

Bartholin cysts are located

lower vestibule adjacent to vaginal canal

2

HPV subtypes
low risk
high risk

low risk: HPV 6 or 11
high risk: 16, 18, 31, 33

3

Condyloma etiology

HPV 6 or 11

4

HPV-infected cells histology

koilocytes--coiled nuclei
"raisinoid" nuclei

5

Lichen sclerosis

thin epidermis with hypertrophy of dermis
occurs in leukoplakia area
slightly increased risk for squamous cell carcinoma

6

Lichen simplex chronicus

hyperplastic epidermis
2˚ to chronic irritation and scratching
leukoplakia with thicker, leathery skin
no increased risk for squamous cell caricnoma

7

Lichen sclerosis vs lichen simplex chonicus

scerlosis: thinning of epidermis, increased risk for squamous cell carcinoma
simplex chronicus: thickening of epidermis, increased risk for squamous cell carcinoma
=> both in setting of leukoplakia

8

Non-HPV related squamous cell caricinoma of vulva is caused by what

lichen simplex chronicus
leukoplakia
may be precancerous

9

Non-HPV vulvar carcinoma usually in this population

women > 70
from longstanding lichen sclerosis

10

Extramammary Paget disease
pathology findings

malignant cells found in epidermis
carcinoma in situ
erythemitis, pruritic, ulcerated vulvar skin

11

Extramammary Paget disease vs Paget disease of nipple

both caricnoma in situs
Paget of nipple has underlying breast caricnoma under it
extramammary Paget is standalone in situ carcinoma

12

Extramammary Paget distringuished from what other entity

melanoma

13

How to differentiate extramammary Paget and melanoma

Paget: keratin +, S100-, PAS+
Melanoma: keratin -, S100+, PAS-

14

PAS stain stains for what

mucus secreting cells
only in epithelial tissue ie Paget