enzyme kinetics

Question 1

michaelic menten model

Answer 1

explains how the rate of an enzyme-catalysed reaction depends on the concentration of the enzyme and its substrate

Question 2

k1

Answer 2

is the forward rate constant for enzyme association with the substrate

Question 3

k-1

Answer 3

the backwards rate constant for enzyme dissociation from the substrate

Question 4

k2

Answer 4

the forward rate constant of enzyme conversion of substrate to product (P)

Question 5

vmax

Answer 5

maximal rate of enzyme catalisation

Question 6

km

Answer 6

half vmax

Question 7

linewweaver burkplot

Answer 7

enables accurate determination of vmax and km

Question 8

low km meaning

Answer 8

enzyme
only needs a little substrate to
work at half-maximal velocity

Question 9

high km

Answer 9

an enzyme
needs a lot of substrate to work at
half-maximal velocity

Question 10

can enzymes display the same vmax and have different km

Answer 10

yes

Question 11

do allosteric enzymes follow michaelic menten

Answer 11

no

Question 12

curve on graph of allosteric enzymes

Answer 12

sigmoidal- s shaped insetad of hyperbola

Question 13

example of allosteric regulation

Answer 13

oxygen to haemoglobin binding