Enzymes Flashcards
(13 cards)
How does a substrate bind to an enzyme?
Through its active site
The active site is _____ to the substrate (2)
- high affinity
- specific
Does the addition of an enzyme lower the activation energy?
Yes
What happens when all active sites of the enzyme are occupied?
The enzyme is saturated
How does increased substrate concentration effect enzyme reaction rate?
Enzyme reaction rates increases
After an enzyme is saturated, how does additional substrate affect the rate of reaction?
It doesn’t, enzyme reaction rate doesn’t change
Name the three types of inhibition
- competitive
- non competitive
- feedback
What is competitive inhibition?
This occurs when an inhibitor molecule binds to the active site of the enzyme and stops the substrate from binding
How can competitive inhibition be avoided?
Increasing the substrate concentration
What is non-competitive inhibition?
This occurs when an inhibitor does not bind to the active site but does bind to a different part of the enzyme and changes the active sites shape
What are the results of non-competitive inhibition?
Reaction rate decreases as the substrate is prevented from binding
What is feedback inhibition?
This is when the be product in a metabolic pathway binds to an enzyme at the start of the pathway
What are the results of feedback inhibition?
Stops the metabolic pathway until the end product decreases in concentration
