Epilepsy Flashcards

1
Q

What is a seizure?

A

A sudden, irregular discharge of electrical activity in the brain, causing a physical manifestation such as sensory disturbance, unconsciousness, or convulsions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is a convulsion?

A

Uncontrolled shaking molecules of the body due to rapid and repeated contraction and relaxation of muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is an aura?

A

A perceptual disturbance experienced by some prior to a seizure, e.g. a strange light, unpleasant smell, confusing thoughts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is epilepsy?

A

A neurological disorder marked by sudden recurrent episodes of sensory disturbance, LOC, or convulsions, associated with abnormal electrical activity in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

When can epilepsy be diagnosed when there is only a single episode?

A

If high underlying risk through past medical history or family history

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is status epilepticus?

A

Epileptic seizures occuring continuously without recovery of consciousness in between

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What broad categories are seizures categorised into?

A
  • Partial, or focal
  • Generalised
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are focal seizures categorised into?

A
  • Simple
  • Complex
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are generalised seizures classified into?

A
  • Absense
  • Myoclonic
  • Tonic-clonic
  • Tonic
  • Atonic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the difference between focal and generalised seizures?

A

In focal, a small area of the brain is involved. In generalised, the whole brain is involved

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is meant by a simple partial seizure?

A

One where there is no loss of consciousness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is meant by a complex partial seizure?

A

One where consciousness is impaired

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the types of epilepsies causing partial seizures?

A
  • Temporal lobe epilepsy
  • Frontal lobe epilepsy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

When does temporal lobe epilepsy present?

A

In the 1st/2nd decade in most people

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What does temporal lobe epilepsy follow?

A

Seizure with fever, or early injury to the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What auras might you get with temporal lobe epilepsy?

A
  • Auditory hallucinations
  • Rush of memories
17
Q

What are the stages of tonic clonic seizures?

A
  • 1st part is tonic
  • 2nd part is clonic
18
Q

What happens in myoclonic seizures?

A

Brief, shock-like muscle jerks

19
Q

What happens in atonic seizures?

A

Drop attacks

20
Q

What investigations are done in epilepsy?

A
  • Clinical history
  • EEG
  • MRI
21
Q

What information is needed about before the seizure in the clinical history?

A
  • PMH
  • Family history
  • Aura
  • First sign/symptom
22
Q

What information about during the seizure is required in the clinical history?

A
  • Description of seizure
  • Duration
  • Abrupt or gradual end
23
Q

What information about after the seizure is required in the clinical history?

A
  • Post-ictal state
  • Tongue biting
  • Incontinence
  • Neurological deficit
24
Q

What are the vascular differential diagnoses for epilepsy?

A
  • Stroke
  • TIA
25
What are the infectious differential diagnoses for epilepsy?
* Abscess * Meningitis
26
What are the traumatic different diagnoses for epilepsy?
Intracranial haemorrhage
27
What are the autoimmune differential diagnoses for epilepsy?
SLE
28
What are the metabolic differential diagnoses for epilepsy?
* Hypoxia * Electrolyte imbalance * Hypoglycaemia * Thyroid dysfunction
29
What are the iatrogenic differential diagnoses for epilepsy?
* Drugs * Alcohol withdrawal
30
What are the neoplastic differential diagnoses for epilepsy?
Intracerebral mass
31
What is the use of the EEG in epilepsy?
*It is not diagnostic,* but supports the diagnosis
32
What should be assessed using EEG after the first unprovoked seizure?
The risk of seizure recurrence
33
How is the risk of seizure reoccurence assessed on the EEG?
Looking for unequivocal epileptiform activity
34
What does the standard EEG assessment involve?
Photic stimulation and hyperventilation
35
When should an EEG not be used?
* Probably syncope * Clinical presentation supports diagnostic of non-epileptic event
36
Why should EEGs not be used if there is probably syncope?
Risk of false positive result
37
Can EEG be used in isolation to diagnose epilepsy?
No
38
What actions should you consider taking if the EEG is unclear?
* Repeated standard EEGs * Sleep EEGs * Long-term video or ambulatory EEG