Epilepsy Flashcards

(30 cards)

1
Q

What is ictus?

A

any acute event, refers to the epilepsy attack itself

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Aetiology of epilepsy?

A
trauma
hypoxia
pyrexia
mass lesion in skull
drugs
CNS infections
vascular abnormalities
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are the main neurotransmitters involved in epilepsy?

A

GABA (inhibitory) and glutamate (excitatory)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

in simple partial seizure, does patient remain conscious or lose consciousness?

A

remains

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what are deja vu and jamais vu examples of

A

complex partial seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

treatment of absence seizures?

A

pals –> sodium valproate and ethosuxamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

side effects of sodium valproate?

A

gerry little side effects
10% will have hair loss
reduces efficacy of COCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Childhood onset
Patient stares
May go pale
may be noticed by teacher in school?

A

absence seizure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what happens during tonic phase of a seixzure?

A
Rigid
Epileptic cry 
Tongue biting 
Incontinence 
Hypoxia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how long does tonic phase last?

A

10-60 seconds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what happens during clonic phase

A
  • Convulsions
  • Eye rolling
  • Tachycardia
  • No breathing
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

status epileptics is a seizure lasting ?

A

over 30 minutes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

when would you do a CT scan?

A

if you think its a stroke
focal signs
head injury with seizure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

driving - how long can you not drive for after seizure ?

A

6 months

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

if you have a seizure, how long can you not drive a HGV?

A

5 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how long seizure free before driving a car?

A

12 months, or 3 years during sleep

17
Q

how long do you have to be seizure free for and off medication to drive a HGV?

18
Q

what is encephalitis?

A

inflammation of the brain parenchyma

19
Q

most common cause of encephalitis?

A

herpes simplex virus

20
Q

does sodium valproate cause weight gain or weight loss?

21
Q

what can they do to the efficacy of the pill?

22
Q

precipitants of status epilepticus?

A
Severe metabolic disorders
 hyponatraemia, pyridoxine deficiency
Infection
Head trauma
Sub-arachnoid haemorrhage
Abrupt withdrawl of anti-convulsants Treating absence seizures with CBZ
23
Q

management of status epilepticus?

A
ABC 
Emergency blood tests +/- CT 
Anti convulsants ( Phenytoin (check levels)
Keppra
valproate
Benzodiazepines)
24
Q

side effects of ethosuxamide?

A

diziness, nausea, anorexia

25
1st line for focal/partial seizures?
carbamazepine
26
side effects of carbamazepine?
diziness, GI disturbance, water retention, SKIN RASH
27
main side effect of digoxin?
blurred vision
28
which drug causes gum hypertrophy?
phenytoin, which is also teratogenic and causes arrhythmias
29
method of action of lamotrigine?
inhibits sodium channels
30
side effects of lamotrigine?
han (nausea, diziness, ataxia)