Epinephrine 1:1000 & 1:10,000 (Adrenalin) Flashcards Preview

Paramedic Drugs Set 4 - Hypotension / Bradycardia > Epinephrine 1:1000 & 1:10,000 (Adrenalin) > Flashcards

Flashcards in Epinephrine 1:1000 & 1:10,000 (Adrenalin) Deck (7)
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1

Classification

Sympathomimetic, adrenergic agent, inotropic

2

Mechanism of Action

  • Binds strongly with both alpha & beta receptors
  • Increases heart rate & automaticity
  • Increases cardiac contractile force
  • Increases myocardial electrical activity
  • Increases systemic vascular resistance
  • Increases blood pressure
  • Bronchodilation

3

Indications

  • Bronchial Asthma
  • Exacerbation of COPD
  • Allergic reactions & anaphylaxis
  • Restoration of cardiac activity in cardiac arrest

4

Contraindications

  • Arrythmias other than VF, asystole, or PEA
  • Cardiovascular disease
  • Hypertension
  • Cerebrovascular disease
  • Shock, secondary to causes other than anaphylactic shock
  • Closed angle glaucoma
  • Diabetes
  • Pregnant women in active labor
  • Known hypersensitivity to epinephrine or sulfites

5

Adverse Effects

  • Palpitations, tachycardia, anxiousness, headache, tremor, chest pain

6

Administration

  • Cardiac Arrest
    • Adult: 1 mg (1:10,000) IV/IO, repeat Q3-5 minutes.
    • Pediatrics: 0.01 mg/kg (1:10,000) IV/IO, repeat Q3-5 minutes, max dose 1 mg.
  • Symptomatic Bradycardia 
    • ​Adult: 1 mcg/min (1:10,000) as continous IV infusion; usual dose range 2-10 mcg/min IV, titrate to effect.
    • Pediatric: 0.01 mg/kg (1:10,000) IV/IO, repeat Q3-5 minutes, max dose 1 mg.
  • Asthma Attacks & Certain Allergic Reactions
    • Adult: 0.3-0.5 mg (1:1,000) IM or SubQ, may repeat every 10-15 minutes. max dose 1 mg
    • Pediatrics: 0.01 mg/kg (1:1,000) IM/SubQ, max  dose 0.5 mg
  • Anaphylactic Shock
    • Adult: 0.1 mg (1:10,000) IV slowly over 5 minutes or IV infusion of 1-4 mcg/min, titrate to effect.
    • Pediatrics: Continous IV infusion rate of 0.1-1 mcg/kg/min (1:10,000), titrate to effect.

7

Special Considerations

  • Half life is one minute