EXAM #1: ABNORMAL GROWTH OF PEDS Flashcards Preview

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Flashcards in EXAM #1: ABNORMAL GROWTH OF PEDS Deck (22):
1

What is the normal weight-for-height?

2.3rd - 97.7th percentile

2

What are the abnormal BMIs for children?

Overweight: 85th-95th
Obese= 96th+
Underweight= less than 3rd

3

What causes a US/LS?

1) Turner Syndrome
2) Rickets
3) Achondroplasia

4

What causes a decreased US/LS?

Marfan Syndrome

5

What is the definition of Failure to Thrive?

- Weight less than 2nd percentile
- Decreased velocity of weight gain

*Underlying cause is INSUFFICIENT NUTRITION

6

What is the difference between wasting and stunting?

Wasting= low weight for height

Stunting= low height for age

7

What indicates an abnormally tall child?

1) Height greater than 97.7 %
2) Deviation upward 2 height % curves

*Note that mid-parental height, advanced bone age, and dysmorphic features are also indications for a problem.

8

What is bone age? How is this measurement taken?

- Left hand and wrist x-ray taken and evaluated
- Radiologist gives new age

*This number is then used as a correction in the growth plot

9

What is the most common cause of overgrowth in infancy?

Maternal DM

10

Aside from maternal DM, what are the two most common causes of infant overgrowth?

1) Sotos Syndrome
2) Beckwith-Wiedemann Syndrome

11

What is familial tall stature?

Simply a tall family (no pathology)

12

What is the difference between central and peripheral precocious puberty?

Central= neuro

Peripheral= gonad related

13

What are the symptoms of precocious puberty?

1) Advanced bone age
2) Early epiphyseal closure
3) Tall child that turns out to be short adult

14

What is the most reliable measurement for gigantism?

IGFBP-3

15

What is meant by "eunchoid proportions?"

- Long legs
- Reduced UL segment ratio
- Low sitting height

16

What is the phenotype of melanocortin-4 receptor mutations?

Obesity

17

What is the genetic basis for Klinefelter's Syndrome

2+ X chromosomes in males

18

What is the typical phenotype of a 47 XYY patient?

Autism-like

19

What is a major clinical difference between Marfan Sydrome and Homocystinuria?

Marfan= lens subluxed upward

Homocystinuria= lens subluxed downward
- Also, intellectual disability

20

What is the definition of a short child?

Height less than 2.3rd%

21

How does constitutional delay differ from familial short stature?

Familial= short parents--kid will be short

Constitutional delay= kid just takes a long time to reach normal height

22

What condition should any short girl be worked up for?

Turner's Syndrome