exam 1d Flashcards
(15 cards)
3 components of a nucleotide
ribose (sugar), base, phosphate
DNA backbone is formed by
sugar and phosphate groups
purines
A and G
pyrimidines
C and T
DNA karyotyping
technique that allows researchers observe any abnormality in chromosomes
gene
is a segment of DNA that contains the instruction to make a particular protein or RNA molecule
introns
unlike exons, intron sequences do not code for proteins. Intron play a regulatory role in gene expression
DNA replication and separation
DNA replicated in the interphase of the cell cycle, while the replicated DNA is separated in the mitosis phase of the cell cycle
telomere
a compound structure at the end of a chromosome
replication origin
particular sequence in a genome at which replication is initiated
centromere
the region of a chromosome to which the microtubules of the spindle attach, via the kinetochore, during cell division.
nucleosomes
are formed to compact DNA and that histone proteins are involved in the formation of nucleosomes
histone tails
are subjected to many chemical modifications to regulate the binding between the histone proteins and DNA, which in turn regulate gene expression
different levels of chromosome packing
nucleosome, chromatin fiber, loop
different combinations of histone tail modifications can
confer a specific meaning on the stretch of chromatin on which they occur