Exam 2

Question 1

Mood stabilizer good for Manic

Answer 1

Lithium
VPA
SGA

Question 2

Can get ECT with manic when on

Answer 2

Li + AED + AED
or
Li + APS + AED

Question 3

First line hypomania

Answer 3

Li or VPA or SGA or carbamazepine

Question 4

Mood stabilizers good for depression

Answer 4

Lithium, quetiapine, lurasidone

Question 5

After optimized mood stabilizer / adding what can be done in depressive episode

Answer 5

Add carbamazepine or anti depressant

Question 6

Others you can consider in depression

Answer 6

Olanzapine/Fluoxetine
Lamotrigine
Valproate

Question 7

Need to be on what in depressive state to get ECT

Answer 7

Li +Lamotrigine + AD
or
Li + Quetiapine + AD

Question 8

Manic general drugs

Answer 8

1st line lithium
carba (or Ox)
SGAs + Halo + chloro
Benzo (loraz, clonaz if needed)

Question 9

Mixed in general

Answer 9

Divalproex sodium

Question 10

Maintenance general

Answer 10

1st line Lithium
Can do divalproex sodium
Lamotrigine (good to prevent depression)
Aripiprazole, olanzapine, asenapine, risperidone,
LAI Halo + Fluphen

Question 11

Depression general

Answer 11

2nd line Lithium in BP II
Quetiapine, Lurasidone, Olanzapine/Fluoxetine, carbamazepine

Question 12

GAD 1st line

Answer 12

Escitalopram
Paroxetine
Sertraline

Duloxetine
Venlafaxine XR

Pregabalin

Question 13

GAD 1st line FDA approved

Answer 13

Escitalopram
Paroxetine

Duloxetine
Venlafaxine ER

Question 14

GAD 2nd line FDA approved

Answer 14

Buspirione

Question 15

Panic disorder 1st line

Answer 15

Citalopram
Escitalopram
Fluoxetine
Fluvoxamine
Paroxetine
Sertraline

Venlafaxine XR

Question 16

Panic disorder 1st line FDA approved

Answer 16

Fluoxetine
Paroxetine
Sertraline

Venlafaxine XR

Question 17

SAD 1st line

Answer 17

Escitalopram
Fluvoxamine
Paroxetine
Sertraline
Venlafaxine
Pregabalin

Question 18

SAD 1st line FDA approved

Answer 18

Paroxetine
Sertraline
Venlafaxine XR

Question 19

PTSD 1st line

Answer 19

Fluoxetine
Paroxetine
Sertraline
Venlafaxine

Question 20

PTSD 1st line FDA approved

Answer 20

Paroxetine
Sertraline

Question 21

OCD 1st line

Answer 21

Citalopram
Escitalopram
Fluoxetine
Fluvoxamine
Paroxetine
Sertraline
Clomipramine

Question 22

OCD 1st line FDA approved

Answer 22

Fluoxetine
Fluvoxamine
Paroxetine
Sertraline

Question 23

Sinemet

Answer 23

Carbidopa/Levodopa

Question 24

Minimum carbidopa dose

Answer 24

70-100mg QD

Question 25

Stalveo

Answer 25

Carbidopa/Levodopa/Entacapone

Question 26

COMT inhibitors

Answer 26

Entacapone Tolcapone

Question 27

Entacapone dose

Answer 27

200 with each Carbidopa/Levodopa dose

Question 28

Levodopa starting dose

Answer 28

200-300mg in divide doses

Question 29

Carbidopa/Levodopa ratio of dose

Answer 29

1:4

Question 30

Inbrija

Answer 30

inhaled levodopa

Question 31

MAOi-Bs

Answer 31

Selegiline Rasagiline Safinamide

Question 32

Ergots

Answer 32

Bromocriptine Pergolide Cabergoline

Question 33

Wearing off effect - solution

Answer 33

increase frequency add MAOi add COMT

Question 34

Off, no on - solution

Answer 34

take on empty stomach, ODT, APO SQ

Question 35

Delayed onset - solution

Answer 35

take on empty stomach, water, avoid protein Get some IR

Question 36

Peak effect dyskinesia

Answer 36

Decrease dose switch to CR

Question 37

drug induced psychosis get rid of

Answer 37

anti cholinergic D/c taper amantadine Selegiline taper and D/c DA decrease dopa end of day dose and d/c COMT Add SGAs Quetiapine clozapine Pimavanserin

Question 38

Hallmarks of dementia

Answer 38

beta amyloid plaques and neurofibrillary tangles

Question 39

Hippocampus

Answer 39

short term to long term

Question 40

Hypothalamus

Answer 40

monitors certain activities and controls body's internal clock

Question 41

Thalamus

Answer 41

sensory and limbic information to send to cerebral cortex

Question 42

Limbic system

Answer 42

controls emotions and instinctive behavior

Question 43

Approved drugs for dementia

Answer 43

Donepezil Rivastigmine Galantamine Memantine

Question 44

Namzaric

Answer 44

Memantine + Donepezil

Question 45

Targets for new Alzheimer's drugs

Answer 45

Block B-secretase block gamma secretase Increase A-secreatase to out compete B Increase likelihood of APP processing by A-secreatase Immunization enhance proteolytic degradation