Schizophrenia Flashcards

(74 cards)

1
Q

More EPS FGA or SGA?

A

FGA

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2
Q

Chlorpromazine FGA or SGA?

A

FGA

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3
Q

Fluphenazine FGA or SGA?

A

FGA

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4
Q

Haloperidol FGA or SGA?

A

FGA

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5
Q

Perphenazine FGA or SGA?

A

FGA

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6
Q

Thioridazine FGA or SGA?

A

FGA

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7
Q

Thiothixenne FGA or SGA?

A

FGA

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8
Q

Aripiprazole FGA or SGA?

A

SGA

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9
Q

Asenapine FGA or SGA?

A

SGA

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10
Q

Brexpiprazole FGA or SGA?

A

SGA

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11
Q

Cariprazine FGA or SGA?

A

SGA

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12
Q

Clozapine FGA or SGA?

A

SGA

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13
Q

Iloperidone FGA or SGA?

A

SGA

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14
Q

Lumateperone FGA or SGA?

A

SGA

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15
Q

Lurasidone FGA or SGA?

A

SGA

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16
Q

Olanzapine FGA or SGA?

A

SGA

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17
Q

Paliperidonee FGA or SGA?

A

SGA

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18
Q

Pimavanserin FGA or SGA?

A

SGA

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19
Q

Quetiapine FGA or SGA?

A

SGA

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20
Q

Risperidone FGA or SGA?

A

SGA

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21
Q

Ziprasidone FGA or SGA?

A

SGA

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22
Q

High potency FGA have

A

High EPS
Low Anticholinergic

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23
Q

Low potency FGA have

A

Low EPS
High Anticholinergic

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24
Q

High potency FGA are

A

Fluphenazine
Haloperidol

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25
Low potency FGA are
Thioridazine Chlorpromazine
26
Acute injectable FGA
Chlorpromazine Haloperidol Fluphenazine
27
Long acting injectable FGA
Fluphenazine Haloperidol
28
Acute injectable SGA
Olanzapine Ziprasidone
29
Long acting injectable SGA
Aripiprazole Olanzapine Risperidone Paliperidone
30
Aripiprazole main clinical pearl
Impulsivity
31
Asenapine main clinical pearl
New topical patch available
32
Brexpiprazole main clinical pearl
Impulsivity
33
Clozapine main clinical pearl
Blood dyscrasia Metabolic Constipation QT prolongation Seizure
34
Iloperidone main clinical pearl
Orthostatic hypotension Slow titration
35
Lurasidone main clinical pearl
do not use with strong CYP3A4 inhibitor and inducer
36
Lumateperone main clinical pearl
Don't take in 3rd trimester
37
Olanzapine main clinical pearl
Metabolic risks DRESS
38
Paliperidone main clinical pearl
EPS Prolactin
39
Pimavanserin main clinical pearl
No dopamine
40
Quetiapine main clinical pearl
Sedation Anticholinergic effects Cataracts
41
Risperidone main clinical pearl
EPS Prolactin
42
Ziprasidone main clinical pearl
QT prolongation
43
SGA with Black box warning for suicidal thoughts
Aripiprazole Lurasidone Olanzapine Paliperidone Quetiapine Risperidone
44
APS Sedation AEs
Chlorpromazine Clozapine Quetiapine Thioridazine
45
APS EPS AEs
Chlorpromazine Fluphenazine Haloperidol Perphenazine Thioridazine Thiothixene
46
APS Anticholinergic AEs
Chlorpromazine Clozapine Thioridazine
47
APS Orthostasis AEs
Chlorpromazine Clozapine Iloperidone Thioridazine
48
APS Weight gain AEs
Clozapine Olanzapine
49
APS Prolactin AEs
Chlorpromazine Fluphenazine Haloperidol Paliperidone Perphenazine Risperidone Thioridazine Thiothixene
50
APS Cardiovascular AEs
Haloperidol Chlorpromazine Clozapine Iloperidone Ziprasidone
51
Painful prolonged muscle contractions, involuntary facial movements, arms
Acute dystonias
52
Bradykinesia, tremor, pill rolling
Pseudo-parkinsonism
53
Restlessness, pacingm shuffling
Akathisia
54
Tongue thrusting, chewing, lip smacking
Tardive dyskinesia
55
Acute dystonia treatment
Anti cholinergics IM benzos Decrease dose or d/c
56
Pseudo-parkinsonism treatment
Anti cholinergic Decrease dose or d/c
57
Akathisia treatment
Beta blockers Decrease dose or d/c
58
Tardive dyskinesia treatment
Prevention D/c Do not use anticholinergics because they will mask sxs
59
Quitting smoking can ____ clozapine levels
Increase
60
How to calculate ANC
ANC = WBC * (Segs+Bands) x 1000
61
REMs APS Double Check
Olanzapine Clozapine
62
Class FGA AEs
EPS QTc Prolactin Derm Photosensitive Blue gray Orthostasis Thermo-regu. BBB = dementia
63
Class SGA AEs
Metabolic QTc Blood dyscrasia Seizure Anti cholinergic Sedation Prolactin Ophthalmic
64
FDA approved FGA for acute psychosis
Chlorpromazine, Haloperidol
65
FDA approved FGA for BPD
Loxapine
66
FDA approved FGA for anxiety
Trifluoperzine
67
FDA approved FGA for Tourette's
Haloperidol
68
FDA approved SGA for bipolar
Aripirazole Asenapine Cariprazine Lumateperone Lurasidone Olanzapine Olanzapine + samidorphan Quetiapine Risperidone Ziprasidone
69
FDA approved SGA for MDD augmentation
Aripiprazole
70
FDA approved SGA for autism
Aripiprazole Risperidone
71
FDA approved SGA for tourette's
Aripiprazole
72
FDA approved SGA for MDD
Brexpiprazole Olanzapine Quetiapine
73
FDA approved SGA for parkinson's disease psychosis
Pimavanserin
74
Can elderly patients with dementia get APS for treatment?
Yes if getting treated for schizophrenia. No for pure dementia treatment