exam 2 Flashcards
(19 cards)
naturally active immunity
artificially active immunity
naturally passive
artificially passive
being infected by pathogen
vaccine
breast milk
receiving treatment with lab prod antibodies
which cell is considered the bridge linking adaptive and innate
Th cell
in the dynamics of blood flow thru capillaries, hydrostatic pressure
is the same as capillary pressure
lymph from most of body returns to circulation at
thoracic duct
list and describe 4 major outcomes of activated compliment
1)chemotaxis C3a, C5a, est gradient that calls cells of immune response
2)opsonization C3b, allows enhancement of phagocytosis
3)inflammation C3A, C5A enhances inflammatory processes
4)lysis C3b. C5b, C6-C9 creates MAC which upsets osmotic balance of pathogens, causing lysis
t-helper cells
cytotoxic T cell
T regulatory cell
delivers signals to B cells
delivers apoptosis signals
dampens immune response
which pathway of complement activation
alternate pathway, lack of complement inhibitors
target of cell-mediated immunity
foreign tissue transplants, some cancer cells, intracellular pathogens that reside in host cell
professional APC
dendritic cells, B cells, macrophages
baroreceptors in cartoid sinus and aortic arch are sensitive to
changes in arterial pressure
which cells express MHC I? which cells express MHC II? what env are sampled by each and what general types of antigens are presented by each and to which cells are these presented
MHC I: on nucleated cells, including APCs, sample intracellular env, present endogenous self, altered self and usually viral antigen, present CD8 and Tc cells
MHC II: only on professional APCS (b cells, macrophages), sample extracellular env, present exogenous antigen (bacteria), presents to CD4 and Tn cells
fever
increases metabolic rate to enhance activity of immune cells
lymphatic capil are more ___ than blood capi
permeable
active v passive
active immunity prod memory cells and passive doesnt
primary and secondary response, include time, strength
primary: lag after exposure to antigen, response not strongest snd doesn’t last long, produces memory cells
secondary: a second exposure to same antigen results in fast response, no lag, is stronger and lasts longer, creates more memory cells
B cells originate and mature in
T cells originate and mature in
bone marrow (mature here too)
bone marrow, mature in thymus
why flow of lymph slows travelling thru node
less afferents, multiple efferents
igM
igA
igE
igD
igG
first antib produced
protects mucosal barriers, in milk
allergies and defend against worms
main antib after second response
