Exam 2 Flashcards
(246 cards)
Osteochondrosis
Process of abnormal bone and cartilage formation
Osteochondritis dissecans (OCD)
Lesions that penetrate the joint surface, creating inflammation and effusion
Bone formation
Chondrocytes form calcified columns in hypertrophic zone
What forms Primary Spongiosa?
Osteoblast using calcified columns
What is the pathophysiology of OCD?
Failure of blood vessels to penetrate the calcified cartilage
Occlusion of canals
Epiphyseal necrosis due to mechanical shearing, stress concentration, blunt trauma, or repeated damage
What is the pathophysiology of OCD at a young age?
Thickened cartilage Cyst-like changes Degeneration of cartilage Uncalcified cartilage not vascularized Cracks in pathological cartilage
What is the pathophysiology of OCD in an adult?
Subchondral fibrosis
Fibrocartilage covers the defect
Sclerosis of subchrondral bone
Osteophyte formation
What is the etiology of OCD?
Genetics
Nutrition
Trauma
Combo of factors
What are the genetic causes of OCD?
Rapid growth potential
familial tendencies
Mostly in males
What are the Nutrition causes of OCD?
Decreased Ca and Increased P Excess zinc Copper deficit Vitamin A and D deficiency High protein diet High caloric intake
What are the clinical signs of OCD?
Insidious to acute onset Lameness Decreased ROM Pain on manipulation Synovial effusion Bog spavin for tarsal crural joint Bilateral
Where do you find Equine OCD?
Tibiotarsal joint (Hock) Stifle Fetlock Cervical vertebrae Shoulder
What is the most common place for Equine OCD?
Tibiotarsal joint
Where do you find Equine OCD in the tibiotarsal joint?
Distal intermediate ridge of the tibia Lateral trochlear ridge Medial trochlear ridge Medial malleolus Lateral malleolus
Where do you find Equine OCD in the stifle?
Lateral trochlear ridge
Medial trochlear ridge
Medial femoral condyle (cyst)
Where do you find Equine OCD in the fetlock?
Sagittal ridge of MC III
Caudal eminence of P1
P1 or MC III cyst
How do you treat Equine OCD?
Rest Intra-articular medication Surgery - Arthrotomy Joint supplements Chondroprotective agents
What are the goals of joint therapy for OCD?
Decrease joint inflammation Decrease cartilage degradation Decrease pain Maintain/improve athletic performance Promote longevity improve quality of life
What are the chondroprotective agents for Equine OCD?
Glucosamine Chondroitin sulfate Hyaluronic acid Polysulfated glycoaminoglycans Anti inflammatory drugs - NSAID, corticosteroids
What are the advanced surgical options for Equine OCD?
Cartilage resurfacing
Osteochondral dowel grafts
Autologous chondrocyte transplantation
Gene therapy
Engineered matrix
Harvested matrix from the abattoir and then decellularized to reduce rejection.
Seed the matrix with chondrocytes
Gene therapy
IL-1 antagonist can insert the antagonist into the joint
What are the advantages of Arthroscopy?
Minimal joint trauma Joint evaluation Remove debris Chip Removal Infection reduced
What are the disadvantages of Arthroscopy?
Equipment cost
Set up time